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Generation of ECG signals from a reaction-diffusion model spatially discretized

We propose a model to generate electrocardiogram signals based on a discretized reaction-diffusion system to produce a set of three nonlinear oscillators that simulate the main pacemakers in the heart. The model reproduces electrocardiograms from healthy hearts and from patients suffering various we...

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Autores principales: Quiroz-Juárez, M. A., Jiménez-Ramírez, O., Vázquez-Medina, R., Breña-Medina, V., Aragón, J. L., Barrio, R. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908715/
https://www.ncbi.nlm.nih.gov/pubmed/31831864
http://dx.doi.org/10.1038/s41598-019-55448-5
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author Quiroz-Juárez, M. A.
Jiménez-Ramírez, O.
Vázquez-Medina, R.
Breña-Medina, V.
Aragón, J. L.
Barrio, R. A.
author_facet Quiroz-Juárez, M. A.
Jiménez-Ramírez, O.
Vázquez-Medina, R.
Breña-Medina, V.
Aragón, J. L.
Barrio, R. A.
author_sort Quiroz-Juárez, M. A.
collection PubMed
description We propose a model to generate electrocardiogram signals based on a discretized reaction-diffusion system to produce a set of three nonlinear oscillators that simulate the main pacemakers in the heart. The model reproduces electrocardiograms from healthy hearts and from patients suffering various well-known rhythm disorders. In particular, it is shown that under ventricular fibrillation, the electrocardiogram signal is chaotic and the transition from sinus rhythm to chaos is consistent with the Ruelle-Takens-Newhouse route to chaos, as experimental studies indicate. The proposed model constitutes a useful tool for research, medical education, and clinical testing purposes. An electronic device based on the model was built for these purposes
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spelling pubmed-69087152019-12-16 Generation of ECG signals from a reaction-diffusion model spatially discretized Quiroz-Juárez, M. A. Jiménez-Ramírez, O. Vázquez-Medina, R. Breña-Medina, V. Aragón, J. L. Barrio, R. A. Sci Rep Article We propose a model to generate electrocardiogram signals based on a discretized reaction-diffusion system to produce a set of three nonlinear oscillators that simulate the main pacemakers in the heart. The model reproduces electrocardiograms from healthy hearts and from patients suffering various well-known rhythm disorders. In particular, it is shown that under ventricular fibrillation, the electrocardiogram signal is chaotic and the transition from sinus rhythm to chaos is consistent with the Ruelle-Takens-Newhouse route to chaos, as experimental studies indicate. The proposed model constitutes a useful tool for research, medical education, and clinical testing purposes. An electronic device based on the model was built for these purposes Nature Publishing Group UK 2019-12-12 /pmc/articles/PMC6908715/ /pubmed/31831864 http://dx.doi.org/10.1038/s41598-019-55448-5 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Quiroz-Juárez, M. A.
Jiménez-Ramírez, O.
Vázquez-Medina, R.
Breña-Medina, V.
Aragón, J. L.
Barrio, R. A.
Generation of ECG signals from a reaction-diffusion model spatially discretized
title Generation of ECG signals from a reaction-diffusion model spatially discretized
title_full Generation of ECG signals from a reaction-diffusion model spatially discretized
title_fullStr Generation of ECG signals from a reaction-diffusion model spatially discretized
title_full_unstemmed Generation of ECG signals from a reaction-diffusion model spatially discretized
title_short Generation of ECG signals from a reaction-diffusion model spatially discretized
title_sort generation of ecg signals from a reaction-diffusion model spatially discretized
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908715/
https://www.ncbi.nlm.nih.gov/pubmed/31831864
http://dx.doi.org/10.1038/s41598-019-55448-5
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