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Remediating reduced memory specificity in bipolar disorder: A case study using a Computerized Memory Specificity Training

OBJECTIVES: Reduced autobiographical memory specificity (rAMS) is a vulnerability factor found across unipolar depression (UD), posttraumatic stress disorder (PTSD), eating disorder, schizophrenia, and bipolar disorder (BD). A group delivered psychological therapy training called Memory Specificity...

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Autores principales: Martens, Kris, Takano, Keisuke, Barry, Tom J., Holmes, Emily A., Wyckaert, Sabine, Raes, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908894/
https://www.ncbi.nlm.nih.gov/pubmed/31747124
http://dx.doi.org/10.1002/brb3.1468
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author Martens, Kris
Takano, Keisuke
Barry, Tom J.
Holmes, Emily A.
Wyckaert, Sabine
Raes, Filip
author_facet Martens, Kris
Takano, Keisuke
Barry, Tom J.
Holmes, Emily A.
Wyckaert, Sabine
Raes, Filip
author_sort Martens, Kris
collection PubMed
description OBJECTIVES: Reduced autobiographical memory specificity (rAMS) is a vulnerability factor found across unipolar depression (UD), posttraumatic stress disorder (PTSD), eating disorder, schizophrenia, and bipolar disorder (BD). A group delivered psychological therapy training called Memory Specificity Training (MeST) remediates rAMS in UD and PTSD, with additional downstream effects on related psychological processes and symptoms. Its impact in BD is unknown. In this case study, we examined the impact of a computerized version of MeST (c‐MeST) on improving AMS and related symptoms and processes in participant with rapid cycling type I BD. METHOD: An experimental case study with an ABA design was used. During baseline (14 days, Phase A), the training phase (nine sessions across 17 days, Phase B), and a 1‐month follow‐up (Phase A), memory specificity, depressive symptoms, and related processes and symptoms were repeatedly measured. RESULTS: Memory specificity increased significantly after the participant completed c‐MeST. Session‐to‐session scores indicated that AMS improved most from the in‐person baseline assessment to the first online session. All other measures of processes and symptoms deteriorated during the training phase but regressed to baseline during follow‐up. CONCLUSION: Memory specificity was improved as indicated by increased AMS from pre‐intervention measurement to 1‐month follow‐up. Other improvements in symptoms were not observed. Rather, some related maladaptive psychological processes and symptoms worsened during the training phase and regressed to baseline during follow‐up.
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spelling pubmed-69088942019-12-20 Remediating reduced memory specificity in bipolar disorder: A case study using a Computerized Memory Specificity Training Martens, Kris Takano, Keisuke Barry, Tom J. Holmes, Emily A. Wyckaert, Sabine Raes, Filip Brain Behav Original Research OBJECTIVES: Reduced autobiographical memory specificity (rAMS) is a vulnerability factor found across unipolar depression (UD), posttraumatic stress disorder (PTSD), eating disorder, schizophrenia, and bipolar disorder (BD). A group delivered psychological therapy training called Memory Specificity Training (MeST) remediates rAMS in UD and PTSD, with additional downstream effects on related psychological processes and symptoms. Its impact in BD is unknown. In this case study, we examined the impact of a computerized version of MeST (c‐MeST) on improving AMS and related symptoms and processes in participant with rapid cycling type I BD. METHOD: An experimental case study with an ABA design was used. During baseline (14 days, Phase A), the training phase (nine sessions across 17 days, Phase B), and a 1‐month follow‐up (Phase A), memory specificity, depressive symptoms, and related processes and symptoms were repeatedly measured. RESULTS: Memory specificity increased significantly after the participant completed c‐MeST. Session‐to‐session scores indicated that AMS improved most from the in‐person baseline assessment to the first online session. All other measures of processes and symptoms deteriorated during the training phase but regressed to baseline during follow‐up. CONCLUSION: Memory specificity was improved as indicated by increased AMS from pre‐intervention measurement to 1‐month follow‐up. Other improvements in symptoms were not observed. Rather, some related maladaptive psychological processes and symptoms worsened during the training phase and regressed to baseline during follow‐up. John Wiley and Sons Inc. 2019-11-20 /pmc/articles/PMC6908894/ /pubmed/31747124 http://dx.doi.org/10.1002/brb3.1468 Text en © 2019 The Authors. Brain and Behavior published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Martens, Kris
Takano, Keisuke
Barry, Tom J.
Holmes, Emily A.
Wyckaert, Sabine
Raes, Filip
Remediating reduced memory specificity in bipolar disorder: A case study using a Computerized Memory Specificity Training
title Remediating reduced memory specificity in bipolar disorder: A case study using a Computerized Memory Specificity Training
title_full Remediating reduced memory specificity in bipolar disorder: A case study using a Computerized Memory Specificity Training
title_fullStr Remediating reduced memory specificity in bipolar disorder: A case study using a Computerized Memory Specificity Training
title_full_unstemmed Remediating reduced memory specificity in bipolar disorder: A case study using a Computerized Memory Specificity Training
title_short Remediating reduced memory specificity in bipolar disorder: A case study using a Computerized Memory Specificity Training
title_sort remediating reduced memory specificity in bipolar disorder: a case study using a computerized memory specificity training
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908894/
https://www.ncbi.nlm.nih.gov/pubmed/31747124
http://dx.doi.org/10.1002/brb3.1468
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