Cargando…
Discovery of Novel Doxorubicin Metabolites in MCF7 Doxorubicin-Resistant Cells
Doxorubicin (DOX) is metabolized to a variety of metabolites in vivo, which has been shown to be associated with cardiotoxicity. We speculate that metabolic processes are also present in tumor cells. A LC-MS/MS method was developed to detect intracellular metabolites. Drug resistant tumor cells with...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909010/ https://www.ncbi.nlm.nih.gov/pubmed/31866863 http://dx.doi.org/10.3389/fphar.2019.01434 |