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The Impact of High-mobility Group Box Mutation of T-cell Factor 4 on Its Genomic Binding Pattern in Non–small Cell Lung Cancer

T-cell factor 4 (TCF-4) is determined to play a crucial role in Wnt/β-catenin signaling pathway activation. The mutations and alternative splice isoforms of TCF-4 can cause cancers and other diseases. The high-mobility group (HMG) box domain of TCF-4 contributes to interacting with DNA motif for tra...

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Detalles Bibliográficos
Autores principales: Su, Hongjian, Qiao, Yahong, Xi, Zhuona, Wang, Jifang, Bao, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909080/
https://www.ncbi.nlm.nih.gov/pubmed/31805518
http://dx.doi.org/10.1016/j.tranon.2019.09.012