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AMPK leads to phosphorylation of the transcription factor Nrf2, tuning transactivation of selected target genes
The transcription factor Nrf2 (nuclear factor (erythroid-derived 2)-like 2) and the kinase AMPK (AMP-activated protein kinase) participate in the cellular adaptive response to redox or energy stress. Despite accumulating evidence for positive cooperativity between both proteins, information about di...
Autores principales: | Matzinger, Manuel, Fischhuber, Katrin, Pölöske, Daniel, Mechtler, Karl, Heiss, Elke H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909106/ https://www.ncbi.nlm.nih.gov/pubmed/31805502 http://dx.doi.org/10.1016/j.redox.2019.101393 |
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