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Missing tumor measurement (TM) data in the search for alternative TM-based endpoints in cancer clinical trials

PURPOSE: Missing data commonly occur in cancer clinical trials (CCT) and may hinder the search for alternative trial endpoints. We consider reasons for missing tumor measurement (TM) data in CCT and how missing TM data are typically handled. We explore the potential impact of missing TM data on pred...

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Detalles Bibliográficos
Autores principales: An, Ming-Wen, Tang, Jun, Grothey, Axel, Sargent, Daniel J., Ou, Fang-Shu, Mandrekar, Sumithra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909186/
https://www.ncbi.nlm.nih.gov/pubmed/31872158
http://dx.doi.org/10.1016/j.conctc.2019.100492