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Missing tumor measurement (TM) data in the search for alternative TM-based endpoints in cancer clinical trials
PURPOSE: Missing data commonly occur in cancer clinical trials (CCT) and may hinder the search for alternative trial endpoints. We consider reasons for missing tumor measurement (TM) data in CCT and how missing TM data are typically handled. We explore the potential impact of missing TM data on pred...
Autores principales: | An, Ming-Wen, Tang, Jun, Grothey, Axel, Sargent, Daniel J., Ou, Fang-Shu, Mandrekar, Sumithra J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909186/ https://www.ncbi.nlm.nih.gov/pubmed/31872158 http://dx.doi.org/10.1016/j.conctc.2019.100492 |
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