CTCF modulates allele-specific sub-TAD organization and imprinted gene activity at the mouse Dlk1-Dio3 and Igf2-H19 domains

BACKGROUND: Genomic imprinting is essential for mammalian development and provides a unique paradigm to explore intra-cellular differences in chromatin configuration. So far, the detailed allele-specific chromatin organization of imprinted gene domains has mostly been lacking. Here, we explored the...

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Detalles Bibliográficos
Autores principales: Llères, David, Moindrot, Benoît, Pathak, Rakesh, Piras, Vincent, Matelot, Mélody, Pignard, Benoît, Marchand, Alice, Poncelet, Mallory, Perrin, Aurélien, Tellier, Virgile, Feil, Robert, Noordermeer, Daan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909504/
https://www.ncbi.nlm.nih.gov/pubmed/31831055
http://dx.doi.org/10.1186/s13059-019-1896-8

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