FXR activation alleviates tacrolimus-induced post-transplant diabetes mellitus by regulating renal gluconeogenesis and glucose uptake

BACKGROUND: Tacrolimus (FK506)-induced diabetes mellitus is one of the most important factors of post-transplant diabetes mellitus (PTDM). However, the detailed mechanisms underlying PTDM are still unclear. Farnesoid X receptor (FXR) regulates glycolipid metabolism. The objective of this study was t...

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Detalles Bibliográficos
Autores principales: Li, Ling, Zhao, Huijia, Chen, Binyao, Fan, Zhipeng, Li, Ning, Yue, Jiang, Ye, Qifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909577/
https://www.ncbi.nlm.nih.gov/pubmed/31836014
http://dx.doi.org/10.1186/s12967-019-02170-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909577/
https://www.ncbi.nlm.nih.gov/pubmed/31836014
http://dx.doi.org/10.1186/s12967-019-02170-5

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