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Upregulation of MUC5AC by VEGF in human primary bronchial epithelial cells: implications for asthma
BACKGROUND: Airway mucus hypersecretion is an important pathophysiological feature in asthma. Mucins are glycoproteins that are mainly responsible for the viscoelastic property of mucus, and MUC5AC is a major mucin glycoprotein that is overproduced in asthma. Vascular endothelial growth factor (VEGF...
Autores principales: | Kim, Sung-Ho, Pei, Qing-Mei, Jiang, Ping, Liu, Juan, Sun, Rong-Fei, Qian, Xue-Jiao, Liu, Jiang-Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909599/ https://www.ncbi.nlm.nih.gov/pubmed/31831011 http://dx.doi.org/10.1186/s12931-019-1245-1 |
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