The effects of long non-coding ribonucleic acids on various cellular components in rheumatoid arthritis

RA is a chronic, autoimmune-mediated inflammatory pathology. Long non-coding RNAs (lncRNAs) are a novel group of non-coding RNAs with a length of >200 nucleotides. There are reports emerging that suggest that lncRNAs participate in establishing and sustaining autoimmune diseases, including RA. In...

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Detalles Bibliográficos
Autores principales: Fang, Yilong, Tu, Jiajie, Han, Dafei, Guo, Yawei, Hong, Wenming, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909907/
https://www.ncbi.nlm.nih.gov/pubmed/31605483
http://dx.doi.org/10.1093/rheumatology/kez472
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author Fang, Yilong
Tu, Jiajie
Han, Dafei
Guo, Yawei
Hong, Wenming
Wei, Wei
author_facet Fang, Yilong
Tu, Jiajie
Han, Dafei
Guo, Yawei
Hong, Wenming
Wei, Wei
author_sort Fang, Yilong
collection PubMed
description RA is a chronic, autoimmune-mediated inflammatory pathology. Long non-coding RNAs (lncRNAs) are a novel group of non-coding RNAs with a length of >200 nucleotides. There are reports emerging that suggest that lncRNAs participate in establishing and sustaining autoimmune diseases, including RA. In this review article, we highlight the functions of lncRNAs in different cell types in RA. Our review indicates that lncRNAs affect various cellular components and are novel candidates that could constitute promising targets for the diagnosis and treatment of RA.
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spelling pubmed-69099072019-12-17 The effects of long non-coding ribonucleic acids on various cellular components in rheumatoid arthritis Fang, Yilong Tu, Jiajie Han, Dafei Guo, Yawei Hong, Wenming Wei, Wei Rheumatology (Oxford) Reviews RA is a chronic, autoimmune-mediated inflammatory pathology. Long non-coding RNAs (lncRNAs) are a novel group of non-coding RNAs with a length of >200 nucleotides. There are reports emerging that suggest that lncRNAs participate in establishing and sustaining autoimmune diseases, including RA. In this review article, we highlight the functions of lncRNAs in different cell types in RA. Our review indicates that lncRNAs affect various cellular components and are novel candidates that could constitute promising targets for the diagnosis and treatment of RA. Oxford University Press 2020-01 2019-10-12 /pmc/articles/PMC6909907/ /pubmed/31605483 http://dx.doi.org/10.1093/rheumatology/kez472 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Rheumatology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Reviews
Fang, Yilong
Tu, Jiajie
Han, Dafei
Guo, Yawei
Hong, Wenming
Wei, Wei
The effects of long non-coding ribonucleic acids on various cellular components in rheumatoid arthritis
title The effects of long non-coding ribonucleic acids on various cellular components in rheumatoid arthritis
title_full The effects of long non-coding ribonucleic acids on various cellular components in rheumatoid arthritis
title_fullStr The effects of long non-coding ribonucleic acids on various cellular components in rheumatoid arthritis
title_full_unstemmed The effects of long non-coding ribonucleic acids on various cellular components in rheumatoid arthritis
title_short The effects of long non-coding ribonucleic acids on various cellular components in rheumatoid arthritis
title_sort effects of long non-coding ribonucleic acids on various cellular components in rheumatoid arthritis
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909907/
https://www.ncbi.nlm.nih.gov/pubmed/31605483
http://dx.doi.org/10.1093/rheumatology/kez472
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