A rare Bombay (Oh) phenotype to 'A' blood group – Live donor liver transplant

Bombay (Oh) phenotype is the rarest blood group in India characterized by the absence of A, B, and H antigens and the presence of anti-H antibodies besides anti-A and anti-B. There is no literature predicting the safety of Oh blood group organ donation to non-Oh blood group recipient. We present the...

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Autores principales: Sachan, Deepti, Saha, Suryatapa, Kumar, Chandan K, Reddy, Srinivas M, Kaliamoorthy, Ilankumaran, Rela, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910029/
https://www.ncbi.nlm.nih.gov/pubmed/31896926
http://dx.doi.org/10.4103/ajts.AJTS_21_18
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author Sachan, Deepti
Saha, Suryatapa
Kumar, Chandan K
Reddy, Srinivas M
Kaliamoorthy, Ilankumaran
Rela, Mohamed
author_facet Sachan, Deepti
Saha, Suryatapa
Kumar, Chandan K
Reddy, Srinivas M
Kaliamoorthy, Ilankumaran
Rela, Mohamed
author_sort Sachan, Deepti
collection PubMed
description Bombay (Oh) phenotype is the rarest blood group in India characterized by the absence of A, B, and H antigens and the presence of anti-H antibodies besides anti-A and anti-B. There is no literature predicting the safety of Oh blood group organ donation to non-Oh blood group recipient. We present the first reported case of successful live donor liver transplantation from an Oh-positive liver donor to an A-positive blood group recipient with hepatitis B virus-related chronic liver disease. The case highlights the need for proper immunohematological workup, national registry of rare group blood donors and need of protocol for perioperative monitoring and blood management in ABO-incompatible organ transplants involving Oh group donor or recipient.
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spelling pubmed-69100292020-01-02 A rare Bombay (Oh) phenotype to 'A' blood group – Live donor liver transplant Sachan, Deepti Saha, Suryatapa Kumar, Chandan K Reddy, Srinivas M Kaliamoorthy, Ilankumaran Rela, Mohamed Asian J Transfus Sci Case Report Bombay (Oh) phenotype is the rarest blood group in India characterized by the absence of A, B, and H antigens and the presence of anti-H antibodies besides anti-A and anti-B. There is no literature predicting the safety of Oh blood group organ donation to non-Oh blood group recipient. We present the first reported case of successful live donor liver transplantation from an Oh-positive liver donor to an A-positive blood group recipient with hepatitis B virus-related chronic liver disease. The case highlights the need for proper immunohematological workup, national registry of rare group blood donors and need of protocol for perioperative monitoring and blood management in ABO-incompatible organ transplants involving Oh group donor or recipient. Wolters Kluwer - Medknow 2019 2019-12-03 /pmc/articles/PMC6910029/ /pubmed/31896926 http://dx.doi.org/10.4103/ajts.AJTS_21_18 Text en Copyright: © 2019 Asian Journal of Transfusion Science http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Sachan, Deepti
Saha, Suryatapa
Kumar, Chandan K
Reddy, Srinivas M
Kaliamoorthy, Ilankumaran
Rela, Mohamed
A rare Bombay (Oh) phenotype to 'A' blood group – Live donor liver transplant
title A rare Bombay (Oh) phenotype to 'A' blood group – Live donor liver transplant
title_full A rare Bombay (Oh) phenotype to 'A' blood group – Live donor liver transplant
title_fullStr A rare Bombay (Oh) phenotype to 'A' blood group – Live donor liver transplant
title_full_unstemmed A rare Bombay (Oh) phenotype to 'A' blood group – Live donor liver transplant
title_short A rare Bombay (Oh) phenotype to 'A' blood group – Live donor liver transplant
title_sort rare bombay (oh) phenotype to 'a' blood group – live donor liver transplant
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910029/
https://www.ncbi.nlm.nih.gov/pubmed/31896926
http://dx.doi.org/10.4103/ajts.AJTS_21_18
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