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Pediatric Pancreatitis: Outcomes and Current Understanding

AIM: The aim of this study was to analyze the clinical spectrum of pediatric pancreatitis and review current literature with regard to concepts of disease and management approaches. MATERIALS AND METHODS: This is a retrospective analysis of pancreatitis patients admitted to a tertiary referral pedia...

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Autor principal: Vepakomma, Deepti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910056/
https://www.ncbi.nlm.nih.gov/pubmed/31896895
http://dx.doi.org/10.4103/jiaps.JIAPS_223_18
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author Vepakomma, Deepti
author_facet Vepakomma, Deepti
author_sort Vepakomma, Deepti
collection PubMed
description AIM: The aim of this study was to analyze the clinical spectrum of pediatric pancreatitis and review current literature with regard to concepts of disease and management approaches. MATERIALS AND METHODS: This is a retrospective analysis of pancreatitis patients admitted to a tertiary referral pediatric surgical unit from March 2013 to September 2018. RESULTS: There were 106 patients from 1 year to 18 years with median age group between 11 and 15 years and equal gender distribution. Sixty-two children had acute pancreatitis (AP), with 13 of them having recurrent episodes. Forty-four patients had chronic pancreatitis (CP). Definite etiology was found in 11 AP patients. All patients had radiological changes. All AP patients were treated symptomatically except those with correctable underlying etiology. Sixteen with CP required intervention in the form of endoscopic retrograde cholangiopancreatography sphincterotomy/stenting or surgery. There were two mortalities. One with acute necrotizing pancreatitis and one CP girl due to the complication of diabetes mellitus, unrelated to episode of pancreatitis. All others are well at the last follow-up. CONCLUSION: Pediatric pancreatitis is a disease with a wide spectrum, but management can be standardized. Newer studies reveal that certain genetic mutations make children more susceptible to pancreatitis. Increasing incidence must prompt us to evaluate further so as to better equip ourselves to managing this disease entity in all its forms and evolve preventive strategies.
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spelling pubmed-69100562020-01-03 Pediatric Pancreatitis: Outcomes and Current Understanding Vepakomma, Deepti J Indian Assoc Pediatr Surg Original Article AIM: The aim of this study was to analyze the clinical spectrum of pediatric pancreatitis and review current literature with regard to concepts of disease and management approaches. MATERIALS AND METHODS: This is a retrospective analysis of pancreatitis patients admitted to a tertiary referral pediatric surgical unit from March 2013 to September 2018. RESULTS: There were 106 patients from 1 year to 18 years with median age group between 11 and 15 years and equal gender distribution. Sixty-two children had acute pancreatitis (AP), with 13 of them having recurrent episodes. Forty-four patients had chronic pancreatitis (CP). Definite etiology was found in 11 AP patients. All patients had radiological changes. All AP patients were treated symptomatically except those with correctable underlying etiology. Sixteen with CP required intervention in the form of endoscopic retrograde cholangiopancreatography sphincterotomy/stenting or surgery. There were two mortalities. One with acute necrotizing pancreatitis and one CP girl due to the complication of diabetes mellitus, unrelated to episode of pancreatitis. All others are well at the last follow-up. CONCLUSION: Pediatric pancreatitis is a disease with a wide spectrum, but management can be standardized. Newer studies reveal that certain genetic mutations make children more susceptible to pancreatitis. Increasing incidence must prompt us to evaluate further so as to better equip ourselves to managing this disease entity in all its forms and evolve preventive strategies. Wolters Kluwer - Medknow 2020 2019-11-27 /pmc/articles/PMC6910056/ /pubmed/31896895 http://dx.doi.org/10.4103/jiaps.JIAPS_223_18 Text en Copyright: © 2019 Journal of Indian Association of Pediatric Surgeons http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Vepakomma, Deepti
Pediatric Pancreatitis: Outcomes and Current Understanding
title Pediatric Pancreatitis: Outcomes and Current Understanding
title_full Pediatric Pancreatitis: Outcomes and Current Understanding
title_fullStr Pediatric Pancreatitis: Outcomes and Current Understanding
title_full_unstemmed Pediatric Pancreatitis: Outcomes and Current Understanding
title_short Pediatric Pancreatitis: Outcomes and Current Understanding
title_sort pediatric pancreatitis: outcomes and current understanding
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910056/
https://www.ncbi.nlm.nih.gov/pubmed/31896895
http://dx.doi.org/10.4103/jiaps.JIAPS_223_18
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