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Perturbations of Ubiquitin-Proteasome-Mediated Proteolysis in Aging and Alzheimer’s Disease

The ubiquitin-proteasome pathway (UPP) has multiple roles in the normal nervous system, including the development of synaptic connections and synaptic plasticity. Research over the past several years has indicated a role for the UPP in aging without any overt pathology in the brain. In addition, mal...

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Detalles Bibliográficos
Autores principales:	Hegde, Ashok N., Smith, Spencer G., Duke, Lindsey M., Pourquoi, Allison, Vaz, Savannah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910070/ https://www.ncbi.nlm.nih.gov/pubmed/31866849 http://dx.doi.org/10.3389/fnagi.2019.00324

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