Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa

OBJECTIVES: The cephalosporin nitric oxide (NO)-donor prodrug DEA-C3D (‘DiEthylAmin-Cephalosporin-3′-Diazeniumdiolate’) has been shown to initiate the dispersal of biofilms formed by the Pseudomonas aeruginosa laboratory strain PAO1. In this study, we investigated whether DEA-C3D disperses biofilms...

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Detalles Bibliográficos
Autores principales: Soren, Odel, Rineh, Ardeshir, Silva, Diogo G, Cai, Yuming, Howlin, Robert P, Allan, Raymond N, Feelisch, Martin, Davies, Jane C, Connett, Gary J, Faust, Saul N, Kelso, Michael J, Webb, Jeremy S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910178/
https://www.ncbi.nlm.nih.gov/pubmed/31682251
http://dx.doi.org/10.1093/jac/dkz378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910178/
https://www.ncbi.nlm.nih.gov/pubmed/31682251
http://dx.doi.org/10.1093/jac/dkz378

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