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Changes in endolysosomal organization define a pre-degenerative state in the crumbs mutant Drosophila retina
Mutations in the epithelial polarity gene crumbs (crb) lead to retinal degeneration in Drosophila and in humans. The overall morphology of the retina and its deterioration in Drosophila crb mutants has been well-characterized, but the cell biological origin of the degeneration is not well understood...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910688/ https://www.ncbi.nlm.nih.gov/pubmed/31834921 http://dx.doi.org/10.1371/journal.pone.0220220 |