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A centrosome-localized calcium signal is essential for mammalian cell mitosis

Mitosis defects can lead to premature ageing and cancer. Understanding mitosis regulation therefore has important implications for human disease. Early data suggested that calcium (Ca(2+)) signals could influence mitosis, but these have hitherto not been observed in mammalian cells. Here, we reveal...

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Detalles Bibliográficos
Autores principales: Helassa, Nordine, Nugues, Charlotte, Rajamanoharan, Dayani, Burgoyne, Robert D., Haynes, Lee P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910830/
https://www.ncbi.nlm.nih.gov/pubmed/31682764
http://dx.doi.org/10.1096/fj.201901662R