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Topology-dependent anomalous dynamics of ring and linear DNA are sensitive to cytoskeleton crosslinking
Cytoskeletal crowding plays a key role in the diffusion of DNA molecules through the cell, acting as a barrier to effective intracellular transport and conformational stability required for processes such as transfection, viral infection, and gene therapy. Here, we elucidate the transport properties...
Autores principales: | Wulstein, Devynn M., Regan, Kathryn E., Garamella, Jonathan, McGorty, Ryan J., Robertson-Anderson, Rae M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910835/ https://www.ncbi.nlm.nih.gov/pubmed/31853502 http://dx.doi.org/10.1126/sciadv.aay5912 |
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