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Interaction of melatonin and Bmal1 in the regulation of PI3K/AKT pathway components and cellular survival
The circadian rhythm is driven by a master clock within the suprachiasmatic nucleus which regulates the rhythmic secretion of melatonin. Bmal1 coordinates the rhythmic expression of transcriptome and regulates biological activities, involved in cell metabolism and aging. However, the role of Bmal1 i...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910929/ https://www.ncbi.nlm.nih.gov/pubmed/31836786 http://dx.doi.org/10.1038/s41598-019-55663-0 |