Converging TLR9 and PI3Kgamma signaling induces sterile inflammation and organ damage

Toll-like receptor 9 (TLR9) and Phosphatidylinositol-3-kinase gamma (PI3Kγ) are very important effectors of the immune response, however, the importance of such crosstalk for disease development is still a matter of discussion. Here we show that PI3Kγ is required for immune responses in which TLR9 i...

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Detalles Bibliográficos
Autores principales: Lima, Braulio Henrique Freire, Marques, Pedro Elias, Gomides, Lindisley Ferreira, Mattos, Matheus Silvério, Kraemer, Lucas, Queiroz-Junior, Celso M., Lennon, Mark, Hirsch, Emilio, Russo, Remo Castro, Menezes, Gustavo Batista, Hessel, Edith M., Amour, Augustin, Teixeira, Mauro Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910931/
https://www.ncbi.nlm.nih.gov/pubmed/31836766
http://dx.doi.org/10.1038/s41598-019-55504-0

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