Routine free thyroxine reference intervals are suboptimal for monitoring children on thyroxine replacement therapy and target intervals need to be assay-specific

Central hypothyroidism is a condition where there is (qualitatively or quantitatively) TSH deficiency, leading to reduced thyroid hormone production. In such patients, serum TSH does not accurately reflect the adequacy of thyroxine replacement, as the log-linear relationship between thyrotropin (TSH...

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Detalles Bibliográficos
Autores principales: Wheeler, Elizabeth, Choy, Kay Weng, Chin, Lit Kim, Wijeratne, Nilika, McNeil, Alan, Yen, Tina, Matthews, Susan, Deam, David, Lu, Zhong, Loh, Tze Ping, Doery, James, Bergman, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910984/
https://www.ncbi.nlm.nih.gov/pubmed/31836869
http://dx.doi.org/10.1038/s41598-019-55690-x

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