Cargando…

Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey

Hyperuricemia and anemia share several comorbidities, but the association between the two conditions remains unclear. The purpose of this study was to investigate the association between hyperuricemia and anemia. Data of 10794 subjects from the Korean National Health and Nutrition Examination Survey...

Descripción completa

Detalles Bibliográficos
Autores principales: Eun, Yeonghee, Han, Kyung-Do, Kim, Da Hye, Kim, In Young, Park, Eun-Jung, Lee, Seulkee, Cha, Hoon-Suk, Koh, Eun-Mi, Lee, Jaejoon, Kim, Hyungjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911023/
https://www.ncbi.nlm.nih.gov/pubmed/31836793
http://dx.doi.org/10.1038/s41598-019-55514-y
_version_ 1783479196129951744
author Eun, Yeonghee
Han, Kyung-Do
Kim, Da Hye
Kim, In Young
Park, Eun-Jung
Lee, Seulkee
Cha, Hoon-Suk
Koh, Eun-Mi
Lee, Jaejoon
Kim, Hyungjin
author_facet Eun, Yeonghee
Han, Kyung-Do
Kim, Da Hye
Kim, In Young
Park, Eun-Jung
Lee, Seulkee
Cha, Hoon-Suk
Koh, Eun-Mi
Lee, Jaejoon
Kim, Hyungjin
author_sort Eun, Yeonghee
collection PubMed
description Hyperuricemia and anemia share several comorbidities, but the association between the two conditions remains unclear. The purpose of this study was to investigate the association between hyperuricemia and anemia. Data of 10794 subjects from the Korean National Health and Nutrition Examination Survey conducted in 2016–2017 were analyzed using multivariate logistic regression analyses. An association between anemia and hyperuricemia was not evident in subjects without chronic kidney disease (CKD). In patients with CKD, anemia increased the risk of hyperuricemia by 2-fold. This association remained significant when adjusting for the glomerular filtration rate. In subgroup analyses, the association of anemia with hyperuricemia was significant in subjects aged ≥65 years, and in those with diabetes or hypertension. Subgroup analyses of CKD patients showed similar results. In the current study using data from Korean representative samples, anemia in subjects with CKD was associated with a 2-fold increase in the risk of hyperuricemia, which remained significant even after adjustment for renal function.
format Online
Article
Text
id pubmed-6911023
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-69110232019-12-16 Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey Eun, Yeonghee Han, Kyung-Do Kim, Da Hye Kim, In Young Park, Eun-Jung Lee, Seulkee Cha, Hoon-Suk Koh, Eun-Mi Lee, Jaejoon Kim, Hyungjin Sci Rep Article Hyperuricemia and anemia share several comorbidities, but the association between the two conditions remains unclear. The purpose of this study was to investigate the association between hyperuricemia and anemia. Data of 10794 subjects from the Korean National Health and Nutrition Examination Survey conducted in 2016–2017 were analyzed using multivariate logistic regression analyses. An association between anemia and hyperuricemia was not evident in subjects without chronic kidney disease (CKD). In patients with CKD, anemia increased the risk of hyperuricemia by 2-fold. This association remained significant when adjusting for the glomerular filtration rate. In subgroup analyses, the association of anemia with hyperuricemia was significant in subjects aged ≥65 years, and in those with diabetes or hypertension. Subgroup analyses of CKD patients showed similar results. In the current study using data from Korean representative samples, anemia in subjects with CKD was associated with a 2-fold increase in the risk of hyperuricemia, which remained significant even after adjustment for renal function. Nature Publishing Group UK 2019-12-13 /pmc/articles/PMC6911023/ /pubmed/31836793 http://dx.doi.org/10.1038/s41598-019-55514-y Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Eun, Yeonghee
Han, Kyung-Do
Kim, Da Hye
Kim, In Young
Park, Eun-Jung
Lee, Seulkee
Cha, Hoon-Suk
Koh, Eun-Mi
Lee, Jaejoon
Kim, Hyungjin
Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey
title Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey
title_full Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey
title_fullStr Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey
title_full_unstemmed Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey
title_short Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey
title_sort association between anemia and hyperuricemia: results from the korean national health and nutrition examination survey
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911023/
https://www.ncbi.nlm.nih.gov/pubmed/31836793
http://dx.doi.org/10.1038/s41598-019-55514-y
work_keys_str_mv AT eunyeonghee associationbetweenanemiaandhyperuricemiaresultsfromthekoreannationalhealthandnutritionexaminationsurvey
AT hankyungdo associationbetweenanemiaandhyperuricemiaresultsfromthekoreannationalhealthandnutritionexaminationsurvey
AT kimdahye associationbetweenanemiaandhyperuricemiaresultsfromthekoreannationalhealthandnutritionexaminationsurvey
AT kiminyoung associationbetweenanemiaandhyperuricemiaresultsfromthekoreannationalhealthandnutritionexaminationsurvey
AT parkeunjung associationbetweenanemiaandhyperuricemiaresultsfromthekoreannationalhealthandnutritionexaminationsurvey
AT leeseulkee associationbetweenanemiaandhyperuricemiaresultsfromthekoreannationalhealthandnutritionexaminationsurvey
AT chahoonsuk associationbetweenanemiaandhyperuricemiaresultsfromthekoreannationalhealthandnutritionexaminationsurvey
AT koheunmi associationbetweenanemiaandhyperuricemiaresultsfromthekoreannationalhealthandnutritionexaminationsurvey
AT leejaejoon associationbetweenanemiaandhyperuricemiaresultsfromthekoreannationalhealthandnutritionexaminationsurvey
AT kimhyungjin associationbetweenanemiaandhyperuricemiaresultsfromthekoreannationalhealthandnutritionexaminationsurvey