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Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey
Hyperuricemia and anemia share several comorbidities, but the association between the two conditions remains unclear. The purpose of this study was to investigate the association between hyperuricemia and anemia. Data of 10794 subjects from the Korean National Health and Nutrition Examination Survey...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911023/ https://www.ncbi.nlm.nih.gov/pubmed/31836793 http://dx.doi.org/10.1038/s41598-019-55514-y |
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author | Eun, Yeonghee Han, Kyung-Do Kim, Da Hye Kim, In Young Park, Eun-Jung Lee, Seulkee Cha, Hoon-Suk Koh, Eun-Mi Lee, Jaejoon Kim, Hyungjin |
author_facet | Eun, Yeonghee Han, Kyung-Do Kim, Da Hye Kim, In Young Park, Eun-Jung Lee, Seulkee Cha, Hoon-Suk Koh, Eun-Mi Lee, Jaejoon Kim, Hyungjin |
author_sort | Eun, Yeonghee |
collection | PubMed |
description | Hyperuricemia and anemia share several comorbidities, but the association between the two conditions remains unclear. The purpose of this study was to investigate the association between hyperuricemia and anemia. Data of 10794 subjects from the Korean National Health and Nutrition Examination Survey conducted in 2016–2017 were analyzed using multivariate logistic regression analyses. An association between anemia and hyperuricemia was not evident in subjects without chronic kidney disease (CKD). In patients with CKD, anemia increased the risk of hyperuricemia by 2-fold. This association remained significant when adjusting for the glomerular filtration rate. In subgroup analyses, the association of anemia with hyperuricemia was significant in subjects aged ≥65 years, and in those with diabetes or hypertension. Subgroup analyses of CKD patients showed similar results. In the current study using data from Korean representative samples, anemia in subjects with CKD was associated with a 2-fold increase in the risk of hyperuricemia, which remained significant even after adjustment for renal function. |
format | Online Article Text |
id | pubmed-6911023 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-69110232019-12-16 Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey Eun, Yeonghee Han, Kyung-Do Kim, Da Hye Kim, In Young Park, Eun-Jung Lee, Seulkee Cha, Hoon-Suk Koh, Eun-Mi Lee, Jaejoon Kim, Hyungjin Sci Rep Article Hyperuricemia and anemia share several comorbidities, but the association between the two conditions remains unclear. The purpose of this study was to investigate the association between hyperuricemia and anemia. Data of 10794 subjects from the Korean National Health and Nutrition Examination Survey conducted in 2016–2017 were analyzed using multivariate logistic regression analyses. An association between anemia and hyperuricemia was not evident in subjects without chronic kidney disease (CKD). In patients with CKD, anemia increased the risk of hyperuricemia by 2-fold. This association remained significant when adjusting for the glomerular filtration rate. In subgroup analyses, the association of anemia with hyperuricemia was significant in subjects aged ≥65 years, and in those with diabetes or hypertension. Subgroup analyses of CKD patients showed similar results. In the current study using data from Korean representative samples, anemia in subjects with CKD was associated with a 2-fold increase in the risk of hyperuricemia, which remained significant even after adjustment for renal function. Nature Publishing Group UK 2019-12-13 /pmc/articles/PMC6911023/ /pubmed/31836793 http://dx.doi.org/10.1038/s41598-019-55514-y Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Eun, Yeonghee Han, Kyung-Do Kim, Da Hye Kim, In Young Park, Eun-Jung Lee, Seulkee Cha, Hoon-Suk Koh, Eun-Mi Lee, Jaejoon Kim, Hyungjin Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey |
title | Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey |
title_full | Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey |
title_fullStr | Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey |
title_full_unstemmed | Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey |
title_short | Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey |
title_sort | association between anemia and hyperuricemia: results from the korean national health and nutrition examination survey |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911023/ https://www.ncbi.nlm.nih.gov/pubmed/31836793 http://dx.doi.org/10.1038/s41598-019-55514-y |
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