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MicroRNA-509-3p inhibits cellular migration, invasion, and proliferation, and sensitizes osteosarcoma to cisplatin

Osteosarcoma (OS) is the most common primary pediatric malignancy of the bone having poor prognosis and long-term survival rates of less than 30% in patients with metastasis. MicroRNA-509 was reported to be downregulated in OS. We and others previously published that miR-509-3p can strongly attenuat...

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Detalles Bibliográficos
Autores principales: Patil, Sagar L., Palat, Asha, Pan, Yinghong, Rajapakshe, Kimal, Mirchandani, Rachna, Bondesson, Maria, Yustein, Jason T., Coarfa, Cristian, Gunaratne, Preethi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911094/
https://www.ncbi.nlm.nih.gov/pubmed/31836741
http://dx.doi.org/10.1038/s41598-019-55170-2