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Molecular basis of arrhythmic substrate in ageing murine peroxisome proliferator-activated receptor γ co-activator deficient hearts modelling mitochondrial dysfunction
Introduction: Ageing and chronic metabolic disorders are associated with mitochondrial dysfunction and cardiac pro-arrhythmic phenotypes which were recently attributed to slowed atrial and ventricular action potential (AP) conduction in peroxisome proliferator-activated receptor γ co-activator defic...
Autores principales: | Edling, Charlotte E., Fazmin, Ibrahim T., Saadeh, Khalil, Chadda, Karan R., Ahmad, Shiraz, Valli, Haseeb, Huang, Christopher L.-H., Jeevaratnam, Kamalan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911157/ https://www.ncbi.nlm.nih.gov/pubmed/31778152 http://dx.doi.org/10.1042/BSR20190403 |
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