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PAD-Beads enrichment enhances detection of PrP(Sc) using real-time quaking-induced conversion

OBJECTIVE: Scrapie is a transmissible spongiform encephalopathy (TSE) that naturally occurs in sheep and goats. This fatal neurodegenerative disease results from misfolding of the normal cellular prion protein (PrP(C)) to a pathogenic prion protein form (PrP(Sc)). This pathogenic form, PrP(Sc), accu...

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Detalles Bibliográficos
Autores principales:	Hwang, Soyoun, Dassanayake, Rohana P., Nicholson, Eric M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911270/ https://www.ncbi.nlm.nih.gov/pubmed/31836019 http://dx.doi.org/10.1186/s13104-019-4842-7

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