Cargando…
Longitudinal trajectories of comorbid PTSD and depression symptoms among U.S. service members and veterans
BACKGROUND: Posttraumatic stress disorder (PTSD) often co-occurs with other psychiatric disorders, particularly major depressive disorder (MDD). The current study examined longitudinal trajectories of PTSD and MDD symptoms among service members and veterans with comorbid PTSD/MDD. METHODS: Eligible...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911296/ https://www.ncbi.nlm.nih.gov/pubmed/31836015 http://dx.doi.org/10.1186/s12888-019-2375-1 |
_version_ | 1783479239104790528 |
---|---|
author | Armenta, Richard F. Walter, Kristen H. Geronimo-Hara, Toni Rose Porter, Ben Stander, Valerie A. LeardMann, Cynthia A. |
author_facet | Armenta, Richard F. Walter, Kristen H. Geronimo-Hara, Toni Rose Porter, Ben Stander, Valerie A. LeardMann, Cynthia A. |
author_sort | Armenta, Richard F. |
collection | PubMed |
description | BACKGROUND: Posttraumatic stress disorder (PTSD) often co-occurs with other psychiatric disorders, particularly major depressive disorder (MDD). The current study examined longitudinal trajectories of PTSD and MDD symptoms among service members and veterans with comorbid PTSD/MDD. METHODS: Eligible participants (n = 1704) for the Millennium Cohort Study included those who screened positive at baseline for both PTSD (PTSD Checklist–Civilian Version) and MDD (Patient Health Questionnaire). Between 2001 and 2016, participants completed a baseline assessment and up to 4 follow-up assessments approximately every 3 years. Mixture modeling simultaneously determined trajectories of comorbid PTSD and MDD symptoms. Multinomial regression determined factors associated with latent class membership. RESULTS: Four distinct classes (chronic, relapse, gradual recovery, and rapid recovery) described symptom trajectories of PTSD/MDD. Membership in the chronic class was associated with older age, service branch, deployment with combat, anxiety, physical assault, disabling injury/illness, bodily pain, high levels of somatic symptoms, and less social support. CONCLUSIONS: Comorbid PTSD/MDD symptoms tend to move in tandem, and, although the largest class remitted symptoms, almost 25% of participants reported chronic comorbid symptoms across all time points. Results highlight the need to assess comorbid conditions in the context of PTSD. Future research should further evaluate the chronicity of comorbid symptoms over time. |
format | Online Article Text |
id | pubmed-6911296 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-69112962019-12-23 Longitudinal trajectories of comorbid PTSD and depression symptoms among U.S. service members and veterans Armenta, Richard F. Walter, Kristen H. Geronimo-Hara, Toni Rose Porter, Ben Stander, Valerie A. LeardMann, Cynthia A. BMC Psychiatry Research Article BACKGROUND: Posttraumatic stress disorder (PTSD) often co-occurs with other psychiatric disorders, particularly major depressive disorder (MDD). The current study examined longitudinal trajectories of PTSD and MDD symptoms among service members and veterans with comorbid PTSD/MDD. METHODS: Eligible participants (n = 1704) for the Millennium Cohort Study included those who screened positive at baseline for both PTSD (PTSD Checklist–Civilian Version) and MDD (Patient Health Questionnaire). Between 2001 and 2016, participants completed a baseline assessment and up to 4 follow-up assessments approximately every 3 years. Mixture modeling simultaneously determined trajectories of comorbid PTSD and MDD symptoms. Multinomial regression determined factors associated with latent class membership. RESULTS: Four distinct classes (chronic, relapse, gradual recovery, and rapid recovery) described symptom trajectories of PTSD/MDD. Membership in the chronic class was associated with older age, service branch, deployment with combat, anxiety, physical assault, disabling injury/illness, bodily pain, high levels of somatic symptoms, and less social support. CONCLUSIONS: Comorbid PTSD/MDD symptoms tend to move in tandem, and, although the largest class remitted symptoms, almost 25% of participants reported chronic comorbid symptoms across all time points. Results highlight the need to assess comorbid conditions in the context of PTSD. Future research should further evaluate the chronicity of comorbid symptoms over time. BioMed Central 2019-12-13 /pmc/articles/PMC6911296/ /pubmed/31836015 http://dx.doi.org/10.1186/s12888-019-2375-1 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Armenta, Richard F. Walter, Kristen H. Geronimo-Hara, Toni Rose Porter, Ben Stander, Valerie A. LeardMann, Cynthia A. Longitudinal trajectories of comorbid PTSD and depression symptoms among U.S. service members and veterans |
title | Longitudinal trajectories of comorbid PTSD and depression symptoms among U.S. service members and veterans |
title_full | Longitudinal trajectories of comorbid PTSD and depression symptoms among U.S. service members and veterans |
title_fullStr | Longitudinal trajectories of comorbid PTSD and depression symptoms among U.S. service members and veterans |
title_full_unstemmed | Longitudinal trajectories of comorbid PTSD and depression symptoms among U.S. service members and veterans |
title_short | Longitudinal trajectories of comorbid PTSD and depression symptoms among U.S. service members and veterans |
title_sort | longitudinal trajectories of comorbid ptsd and depression symptoms among u.s. service members and veterans |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911296/ https://www.ncbi.nlm.nih.gov/pubmed/31836015 http://dx.doi.org/10.1186/s12888-019-2375-1 |
work_keys_str_mv | AT armentarichardf longitudinaltrajectoriesofcomorbidptsdanddepressionsymptomsamongusservicemembersandveterans AT walterkristenh longitudinaltrajectoriesofcomorbidptsdanddepressionsymptomsamongusservicemembersandveterans AT geronimoharatonirose longitudinaltrajectoriesofcomorbidptsdanddepressionsymptomsamongusservicemembersandveterans AT porterben longitudinaltrajectoriesofcomorbidptsdanddepressionsymptomsamongusservicemembersandveterans AT standervaleriea longitudinaltrajectoriesofcomorbidptsdanddepressionsymptomsamongusservicemembersandveterans AT leardmanncynthiaa longitudinaltrajectoriesofcomorbidptsdanddepressionsymptomsamongusservicemembersandveterans AT longitudinaltrajectoriesofcomorbidptsdanddepressionsymptomsamongusservicemembersandveterans |