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Drug Related Hospital Admissions; A Systematic Review of the Recent Literatures

OBJECTIVE: To derive findings from different studies done on drug related hospital admissions and comprehensively express the incidence and preventability of drug related hospital admissions; identify the common types of drug related problems that caused hospital admission, and identify factors asso...

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Autores principales: Ayalew, Mohammed Biset, Tegegn, Henok Getachew, Abdela, Ousman Abubeker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911719/
https://www.ncbi.nlm.nih.gov/pubmed/31857995
http://dx.doi.org/10.29252/beat-070401
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author Ayalew, Mohammed Biset
Tegegn, Henok Getachew
Abdela, Ousman Abubeker
author_facet Ayalew, Mohammed Biset
Tegegn, Henok Getachew
Abdela, Ousman Abubeker
author_sort Ayalew, Mohammed Biset
collection PubMed
description OBJECTIVE: To derive findings from different studies done on drug related hospital admissions and comprehensively express the incidence and preventability of drug related hospital admissions; identify the common types of drug related problems that caused hospital admission, and identify factors associated with drug related hospital admission. METHODS: Literatures that assessed hospitalization due to drug related problems were searched online using Pub Med and Google Scholar databases. The relevant reference lists of retrieved articles were also searched manually on Google. Prospective and retrospective studies conducted anywhere in the world on drug related hospitalization, published from January 2012 to January 2017 as an original article and written in English language were included. RESULT: The prevalence of drug related hospital admission varies from 1.3% to 41.3% with the average rate of 15.4%. Among hospitalized patients 2.7% were died due to drug-related problems (DRPs). Drugs that were frequently reported as causing drug related admission were antithrombotic drugs, antihypertensive drugs, analgesics, anti-diabetics, antipsychotics, and anti-neoplastic drugs. Poly pharmacy, old age and female sex were mentioned as determinants for drug related hospitalization by a number of studies. About one third of drug related hospital admissions were definitely preventable and more than 40% were also potentially preventable. CONCLUSION: Drug related problems contribute for more than 15% of hospital admissions. Higher risk of admission due to DRPs was observed in patients who were on poly pharmacy and those who were old. As most of drug related hospital admissions were preventable an emphasis should be given for preventive strategies to avoid complications and costs associated with admission.
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spelling pubmed-69117192019-12-19 Drug Related Hospital Admissions; A Systematic Review of the Recent Literatures Ayalew, Mohammed Biset Tegegn, Henok Getachew Abdela, Ousman Abubeker Bull Emerg Trauma Review Article OBJECTIVE: To derive findings from different studies done on drug related hospital admissions and comprehensively express the incidence and preventability of drug related hospital admissions; identify the common types of drug related problems that caused hospital admission, and identify factors associated with drug related hospital admission. METHODS: Literatures that assessed hospitalization due to drug related problems were searched online using Pub Med and Google Scholar databases. The relevant reference lists of retrieved articles were also searched manually on Google. Prospective and retrospective studies conducted anywhere in the world on drug related hospitalization, published from January 2012 to January 2017 as an original article and written in English language were included. RESULT: The prevalence of drug related hospital admission varies from 1.3% to 41.3% with the average rate of 15.4%. Among hospitalized patients 2.7% were died due to drug-related problems (DRPs). Drugs that were frequently reported as causing drug related admission were antithrombotic drugs, antihypertensive drugs, analgesics, anti-diabetics, antipsychotics, and anti-neoplastic drugs. Poly pharmacy, old age and female sex were mentioned as determinants for drug related hospitalization by a number of studies. About one third of drug related hospital admissions were definitely preventable and more than 40% were also potentially preventable. CONCLUSION: Drug related problems contribute for more than 15% of hospital admissions. Higher risk of admission due to DRPs was observed in patients who were on poly pharmacy and those who were old. As most of drug related hospital admissions were preventable an emphasis should be given for preventive strategies to avoid complications and costs associated with admission. Shiraz University of Medical Sciences 2019-10 /pmc/articles/PMC6911719/ /pubmed/31857995 http://dx.doi.org/10.29252/beat-070401 Text en © 2019 Trauma Research Center, Shiraz University of Medical Sciences This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ayalew, Mohammed Biset
Tegegn, Henok Getachew
Abdela, Ousman Abubeker
Drug Related Hospital Admissions; A Systematic Review of the Recent Literatures
title Drug Related Hospital Admissions; A Systematic Review of the Recent Literatures
title_full Drug Related Hospital Admissions; A Systematic Review of the Recent Literatures
title_fullStr Drug Related Hospital Admissions; A Systematic Review of the Recent Literatures
title_full_unstemmed Drug Related Hospital Admissions; A Systematic Review of the Recent Literatures
title_short Drug Related Hospital Admissions; A Systematic Review of the Recent Literatures
title_sort drug related hospital admissions; a systematic review of the recent literatures
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911719/
https://www.ncbi.nlm.nih.gov/pubmed/31857995
http://dx.doi.org/10.29252/beat-070401
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