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miR-200 family members reduce senescence and restore idiopathic pulmonary fibrosis type II alveolar epithelial cell transdifferentiation
RATIONALE: Alveolar type II (ATII) cells act as adult stem cells contributing to alveolar type I (ATI) cell renewal and play a major role in idiopathic pulmonary fibrosis (IPF), as supported by familial cases harbouring mutations in genes specifically expressed by these cells. During IPF, ATII cells...
Autores principales: | Moimas, Silvia, Salton, Francesco, Kosmider, Beata, Ring, Nadja, Volpe, Maria C., Bahmed, Karim, Braga, Luca, Rehman, Michael, Vodret, Simone, Graziani, Maria Laura, Wolfson, Marla R., Marchetti, Nathaniel, Rogers, Thomas J., Giacca, Mauro, Criner, Gerard J., Zacchigna, Serena, Confalonieri, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911923/ https://www.ncbi.nlm.nih.gov/pubmed/31857992 http://dx.doi.org/10.1183/23120541.00138-2019 |
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