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Abdominal hernias in cirrhotic patients: Surgery or conservative treatment? Results of a prospective cohort study in a high volume center: Cohort study

BACKGROUND: Surgical treatment of abdominal hernias in cirrhotics is often delayed due to the higher morbidity and mortality associated with the underlying liver disease. Some patients are followed conservatively and only operated on when complications occur (“wait and see” approach). The aim of thi...

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Autores principales: Pinheiro, Rafael Soares, Andraus, Wellington, Waisberg, Daniel Reis, Nacif, Lucas Souto, Ducatti, Liliana, Rocha-Santos, Vinicius, Diniz, Márcio A., Arantes, Rubens Macedo, Lerut, Jan, D'Albuquerque, Luiz Augusto Carneiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911966/
https://www.ncbi.nlm.nih.gov/pubmed/31853365
http://dx.doi.org/10.1016/j.amsu.2019.11.009
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author Pinheiro, Rafael Soares
Andraus, Wellington
Waisberg, Daniel Reis
Nacif, Lucas Souto
Ducatti, Liliana
Rocha-Santos, Vinicius
Diniz, Márcio A.
Arantes, Rubens Macedo
Lerut, Jan
D'Albuquerque, Luiz Augusto Carneiro
author_facet Pinheiro, Rafael Soares
Andraus, Wellington
Waisberg, Daniel Reis
Nacif, Lucas Souto
Ducatti, Liliana
Rocha-Santos, Vinicius
Diniz, Márcio A.
Arantes, Rubens Macedo
Lerut, Jan
D'Albuquerque, Luiz Augusto Carneiro
author_sort Pinheiro, Rafael Soares
collection PubMed
description BACKGROUND: Surgical treatment of abdominal hernias in cirrhotics is often delayed due to the higher morbidity and mortality associated with the underlying liver disease. Some patients are followed conservatively and only operated on when complications occur (“wait and see” approach). The aim of this study is to compare outcomes of cirrhotic patients undergoing conservative non-operative care or elective hernia repair. METHODS: A prospective observational study including 246 cirrhotic patients with abdominal hernia was carried out. Patients were given the option to select their treatment: elective hernia repair or conservative non-operative care. Demographics, characteristics of underlying liver disease, type of hernia, complications and mortality were analyzed. During follow-up of patients who opted for the “wait and see” approach, emergency hernia repair was performed in case of hernia complications. RESULTS: Elective hernia repair was performed in 57 patients and 189 patients were kept in conservative care, of which 43 (22.7%) developed complications that required emergency hernia repair. Elective surgery provided better five-years survival than conservative care (80% vs. 62%; p = 0.012). Multivariate analysis identified multiples hernias [Hazards Ratio (HR):6.7, p < 0.001] and clinical follow-up group (HR 3.62, p = 0.005) as risk factors for mortality. Among patients undergoing surgical treatment, multivariate analysis revealed MELD>11 (HR 7.8; p = 0.011) and emergency hernia repair (HR 5.35; p = 0.005) as independent risk factors for 30-day mortality. CONCLUSIONS: Elective hernia repair offers an acceptable morbidity and ensures longer survival. “Wait and see” approach jeopardizes cirrhotic patients and should be avoided, given the higher incidence of emergency surgery due to hernia complications.
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spelling pubmed-69119662019-12-18 Abdominal hernias in cirrhotic patients: Surgery or conservative treatment? Results of a prospective cohort study in a high volume center: Cohort study Pinheiro, Rafael Soares Andraus, Wellington Waisberg, Daniel Reis Nacif, Lucas Souto Ducatti, Liliana Rocha-Santos, Vinicius Diniz, Márcio A. Arantes, Rubens Macedo Lerut, Jan D'Albuquerque, Luiz Augusto Carneiro Ann Med Surg (Lond) Original Research BACKGROUND: Surgical treatment of abdominal hernias in cirrhotics is often delayed due to the higher morbidity and mortality associated with the underlying liver disease. Some patients are followed conservatively and only operated on when complications occur (“wait and see” approach). The aim of this study is to compare outcomes of cirrhotic patients undergoing conservative non-operative care or elective hernia repair. METHODS: A prospective observational study including 246 cirrhotic patients with abdominal hernia was carried out. Patients were given the option to select their treatment: elective hernia repair or conservative non-operative care. Demographics, characteristics of underlying liver disease, type of hernia, complications and mortality were analyzed. During follow-up of patients who opted for the “wait and see” approach, emergency hernia repair was performed in case of hernia complications. RESULTS: Elective hernia repair was performed in 57 patients and 189 patients were kept in conservative care, of which 43 (22.7%) developed complications that required emergency hernia repair. Elective surgery provided better five-years survival than conservative care (80% vs. 62%; p = 0.012). Multivariate analysis identified multiples hernias [Hazards Ratio (HR):6.7, p < 0.001] and clinical follow-up group (HR 3.62, p = 0.005) as risk factors for mortality. Among patients undergoing surgical treatment, multivariate analysis revealed MELD>11 (HR 7.8; p = 0.011) and emergency hernia repair (HR 5.35; p = 0.005) as independent risk factors for 30-day mortality. CONCLUSIONS: Elective hernia repair offers an acceptable morbidity and ensures longer survival. “Wait and see” approach jeopardizes cirrhotic patients and should be avoided, given the higher incidence of emergency surgery due to hernia complications. Elsevier 2019-11-22 /pmc/articles/PMC6911966/ /pubmed/31853365 http://dx.doi.org/10.1016/j.amsu.2019.11.009 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Research
Pinheiro, Rafael Soares
Andraus, Wellington
Waisberg, Daniel Reis
Nacif, Lucas Souto
Ducatti, Liliana
Rocha-Santos, Vinicius
Diniz, Márcio A.
Arantes, Rubens Macedo
Lerut, Jan
D'Albuquerque, Luiz Augusto Carneiro
Abdominal hernias in cirrhotic patients: Surgery or conservative treatment? Results of a prospective cohort study in a high volume center: Cohort study
title Abdominal hernias in cirrhotic patients: Surgery or conservative treatment? Results of a prospective cohort study in a high volume center: Cohort study
title_full Abdominal hernias in cirrhotic patients: Surgery or conservative treatment? Results of a prospective cohort study in a high volume center: Cohort study
title_fullStr Abdominal hernias in cirrhotic patients: Surgery or conservative treatment? Results of a prospective cohort study in a high volume center: Cohort study
title_full_unstemmed Abdominal hernias in cirrhotic patients: Surgery or conservative treatment? Results of a prospective cohort study in a high volume center: Cohort study
title_short Abdominal hernias in cirrhotic patients: Surgery or conservative treatment? Results of a prospective cohort study in a high volume center: Cohort study
title_sort abdominal hernias in cirrhotic patients: surgery or conservative treatment? results of a prospective cohort study in a high volume center: cohort study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911966/
https://www.ncbi.nlm.nih.gov/pubmed/31853365
http://dx.doi.org/10.1016/j.amsu.2019.11.009
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