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Synaptic biomarkers in CSF aid in diagnosis, correlate with cognition and predict progression in MCI and Alzheimer's disease

INTRODUCTION: Amyloid, Tau, and neurodegeneration biomarkers can stage Alzheimer's Disease (AD). Synaptic biomarkers may help track cognition. METHODS: In cognitively normal controls, Mild Cognitive Impairment (MCI) and AD, we investigated CSF biomarkers in relation to cognitive measures and as...

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Detalles Bibliográficos
Autores principales: Galasko, Douglas, Xiao, Meifang, Xu, Desheng, Smirnov, Denis, Salmon, David P., Dewit, Nele, Vanbrabant, Jeroen, Jacobs, Dirk, Vanderstichele, Hugo, Vanmechelen, Eugeen, Worley, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911971/
https://www.ncbi.nlm.nih.gov/pubmed/31853477
http://dx.doi.org/10.1016/j.trci.2019.11.002

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