TAE226, a dual inhibitor of focal adhesion kinase and insulin‐like growth factor‐I receptor, is effective for Ewing sarcoma

The outcomes for relapsed and metastatic Ewing sarcoma (EWS) is extremely poor. Therefore, it is important to identify the tumor‐specific targets in these intractable diseases. High focal adhesion kinase (FAK) transcript expression levels in EWS cell lines are known. TAE226 is a dual inhibitor of FA...

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Detalles Bibliográficos
Autores principales: Moritake, Hiroshi, Saito, Yusuke, Sawa, Daisuke, Sameshima, Naoki, Yamada, Ai, Kinoshita, Mariko, Kamimura, Sachiyo, Konomoto, Takao, Nunoi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912025/
https://www.ncbi.nlm.nih.gov/pubmed/31692287
http://dx.doi.org/10.1002/cam4.2647

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