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Long non‐coding small nucleolar RNA host genes in digestive cancers

Although long noncoding RNAs (lncRNAs) do not have protein coding capacities, they are involved in the pathogenesis of many types of cancers, including hepatocellular carcinoma, cervical cancer, and gastric cancer. Notably, the roles of lncRNAs are vital in nearly every aspect of tumor biology. Long...

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Detalles Bibliográficos
Autores principales: Yang, Huan, Jiang, Zheng, Wang, Shuang, Zhao, Yongbing, Song, Xiaomei, Xiao, Yufeng, Yang, Shiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912041/
https://www.ncbi.nlm.nih.gov/pubmed/31691514
http://dx.doi.org/10.1002/cam4.2622
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author Yang, Huan
Jiang, Zheng
Wang, Shuang
Zhao, Yongbing
Song, Xiaomei
Xiao, Yufeng
Yang, Shiming
author_facet Yang, Huan
Jiang, Zheng
Wang, Shuang
Zhao, Yongbing
Song, Xiaomei
Xiao, Yufeng
Yang, Shiming
author_sort Yang, Huan
collection PubMed
description Although long noncoding RNAs (lncRNAs) do not have protein coding capacities, they are involved in the pathogenesis of many types of cancers, including hepatocellular carcinoma, cervical cancer, and gastric cancer. Notably, the roles of lncRNAs are vital in nearly every aspect of tumor biology. Long non‐coding small nucleolar RNA host genes (lnc‐SNHGs) are abnormally expressed in multiple cancers, including urologic neoplasms, respiratory tumors, and digestive cancers, and play vital roles in these cancers. These host genes could participate in tumorigenesis by regulating proliferation, migration, invasion and apoptosis of tumor cells. This review focuses on the overview of the roles that lnc‐SNHGs play in the formation and progression of digestive cancers.
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spelling pubmed-69120412019-12-23 Long non‐coding small nucleolar RNA host genes in digestive cancers Yang, Huan Jiang, Zheng Wang, Shuang Zhao, Yongbing Song, Xiaomei Xiao, Yufeng Yang, Shiming Cancer Med Cancer Biology Although long noncoding RNAs (lncRNAs) do not have protein coding capacities, they are involved in the pathogenesis of many types of cancers, including hepatocellular carcinoma, cervical cancer, and gastric cancer. Notably, the roles of lncRNAs are vital in nearly every aspect of tumor biology. Long non‐coding small nucleolar RNA host genes (lnc‐SNHGs) are abnormally expressed in multiple cancers, including urologic neoplasms, respiratory tumors, and digestive cancers, and play vital roles in these cancers. These host genes could participate in tumorigenesis by regulating proliferation, migration, invasion and apoptosis of tumor cells. This review focuses on the overview of the roles that lnc‐SNHGs play in the formation and progression of digestive cancers. John Wiley and Sons Inc. 2019-11-06 /pmc/articles/PMC6912041/ /pubmed/31691514 http://dx.doi.org/10.1002/cam4.2622 Text en © 2019 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cancer Biology
Yang, Huan
Jiang, Zheng
Wang, Shuang
Zhao, Yongbing
Song, Xiaomei
Xiao, Yufeng
Yang, Shiming
Long non‐coding small nucleolar RNA host genes in digestive cancers
title Long non‐coding small nucleolar RNA host genes in digestive cancers
title_full Long non‐coding small nucleolar RNA host genes in digestive cancers
title_fullStr Long non‐coding small nucleolar RNA host genes in digestive cancers
title_full_unstemmed Long non‐coding small nucleolar RNA host genes in digestive cancers
title_short Long non‐coding small nucleolar RNA host genes in digestive cancers
title_sort long non‐coding small nucleolar rna host genes in digestive cancers
topic Cancer Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912041/
https://www.ncbi.nlm.nih.gov/pubmed/31691514
http://dx.doi.org/10.1002/cam4.2622
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