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Long non‐coding small nucleolar RNA host genes in digestive cancers
Although long noncoding RNAs (lncRNAs) do not have protein coding capacities, they are involved in the pathogenesis of many types of cancers, including hepatocellular carcinoma, cervical cancer, and gastric cancer. Notably, the roles of lncRNAs are vital in nearly every aspect of tumor biology. Long...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912041/ https://www.ncbi.nlm.nih.gov/pubmed/31691514 http://dx.doi.org/10.1002/cam4.2622 |
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author | Yang, Huan Jiang, Zheng Wang, Shuang Zhao, Yongbing Song, Xiaomei Xiao, Yufeng Yang, Shiming |
author_facet | Yang, Huan Jiang, Zheng Wang, Shuang Zhao, Yongbing Song, Xiaomei Xiao, Yufeng Yang, Shiming |
author_sort | Yang, Huan |
collection | PubMed |
description | Although long noncoding RNAs (lncRNAs) do not have protein coding capacities, they are involved in the pathogenesis of many types of cancers, including hepatocellular carcinoma, cervical cancer, and gastric cancer. Notably, the roles of lncRNAs are vital in nearly every aspect of tumor biology. Long non‐coding small nucleolar RNA host genes (lnc‐SNHGs) are abnormally expressed in multiple cancers, including urologic neoplasms, respiratory tumors, and digestive cancers, and play vital roles in these cancers. These host genes could participate in tumorigenesis by regulating proliferation, migration, invasion and apoptosis of tumor cells. This review focuses on the overview of the roles that lnc‐SNHGs play in the formation and progression of digestive cancers. |
format | Online Article Text |
id | pubmed-6912041 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-69120412019-12-23 Long non‐coding small nucleolar RNA host genes in digestive cancers Yang, Huan Jiang, Zheng Wang, Shuang Zhao, Yongbing Song, Xiaomei Xiao, Yufeng Yang, Shiming Cancer Med Cancer Biology Although long noncoding RNAs (lncRNAs) do not have protein coding capacities, they are involved in the pathogenesis of many types of cancers, including hepatocellular carcinoma, cervical cancer, and gastric cancer. Notably, the roles of lncRNAs are vital in nearly every aspect of tumor biology. Long non‐coding small nucleolar RNA host genes (lnc‐SNHGs) are abnormally expressed in multiple cancers, including urologic neoplasms, respiratory tumors, and digestive cancers, and play vital roles in these cancers. These host genes could participate in tumorigenesis by regulating proliferation, migration, invasion and apoptosis of tumor cells. This review focuses on the overview of the roles that lnc‐SNHGs play in the formation and progression of digestive cancers. John Wiley and Sons Inc. 2019-11-06 /pmc/articles/PMC6912041/ /pubmed/31691514 http://dx.doi.org/10.1002/cam4.2622 Text en © 2019 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Cancer Biology Yang, Huan Jiang, Zheng Wang, Shuang Zhao, Yongbing Song, Xiaomei Xiao, Yufeng Yang, Shiming Long non‐coding small nucleolar RNA host genes in digestive cancers |
title | Long non‐coding small nucleolar RNA host genes in digestive cancers |
title_full | Long non‐coding small nucleolar RNA host genes in digestive cancers |
title_fullStr | Long non‐coding small nucleolar RNA host genes in digestive cancers |
title_full_unstemmed | Long non‐coding small nucleolar RNA host genes in digestive cancers |
title_short | Long non‐coding small nucleolar RNA host genes in digestive cancers |
title_sort | long non‐coding small nucleolar rna host genes in digestive cancers |
topic | Cancer Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912041/ https://www.ncbi.nlm.nih.gov/pubmed/31691514 http://dx.doi.org/10.1002/cam4.2622 |
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