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Palmitoylation of Hepatitis C Virus NS2 Regulates Its Subcellular Localization and NS2-NS3 Autocleavage
Hepatitis C virus (HCV) nonstructural protein 2 (NS2) is a multifunctional protein implicated in both HCV RNA replication and virus particle assembly. NS2-encoded cysteine protease is responsible for autoprocessing of NS2-NS3 precursor, an essential step in HCV RNA replication. NS2 also promotes HCV...
Autores principales: | Wu, Ming-Jhan, Shanmugam, Saravanabalaji, Welsch, Christoph, Yi, MinKyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912101/ https://www.ncbi.nlm.nih.gov/pubmed/31597774 http://dx.doi.org/10.1128/JVI.00906-19 |
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