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Oligodendrocyte Neurofascin Independently Regulates Both Myelin Targeting and Sheath Growth in the CNS

Selection of the correct targets for myelination and regulation of myelin sheath growth are essential for central nervous system (CNS) formation and function. Through a genetic screen in zebrafish and complementary analyses in mice, we find that loss of oligodendrocyte Neurofascin leads to mistarget...

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Detalles Bibliográficos
Autores principales: Klingseisen, Anna, Ristoiu, Ana-Maria, Kegel, Linde, Sherman, Diane L., Rubio-Brotons, Maria, Almeida, Rafael G., Koudelka, Sigrid, Benito-Kwiecinski, Silvia K., Poole, Richard J., Brophy, Peter J., Lyons, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912162/
https://www.ncbi.nlm.nih.gov/pubmed/31761670
http://dx.doi.org/10.1016/j.devcel.2019.10.016