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Oligodendrocyte Neurofascin Independently Regulates Both Myelin Targeting and Sheath Growth in the CNS
Selection of the correct targets for myelination and regulation of myelin sheath growth are essential for central nervous system (CNS) formation and function. Through a genetic screen in zebrafish and complementary analyses in mice, we find that loss of oligodendrocyte Neurofascin leads to mistarget...
Autores principales: | Klingseisen, Anna, Ristoiu, Ana-Maria, Kegel, Linde, Sherman, Diane L., Rubio-Brotons, Maria, Almeida, Rafael G., Koudelka, Sigrid, Benito-Kwiecinski, Silvia K., Poole, Richard J., Brophy, Peter J., Lyons, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912162/ https://www.ncbi.nlm.nih.gov/pubmed/31761670 http://dx.doi.org/10.1016/j.devcel.2019.10.016 |
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