Cargando…

Rewiring of Cancer Cell Metabolism by Mitochondrial VDAC1 Depletion Results in Time-Dependent Tumor Reprogramming: Glioblastoma as a Proof of Concept

Reprograming of the metabolism of cancer cells is an event recognized as a hallmark of the disease. The mitochondrial gatekeeper, voltage-dependent anion channel 1 (VDAC1), mediates transport of metabolites and ions in and out of mitochondria, and is involved in mitochondria-mediated apoptosis. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Arif, Tasleem, Stern, Oriel, Pittala, Srinivas, Chalifa-Caspi, Vered, Shoshan-Barmatz, Varda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912264/
https://www.ncbi.nlm.nih.gov/pubmed/31661894
http://dx.doi.org/10.3390/cells8111330