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Rewiring of Cancer Cell Metabolism by Mitochondrial VDAC1 Depletion Results in Time-Dependent Tumor Reprogramming: Glioblastoma as a Proof of Concept
Reprograming of the metabolism of cancer cells is an event recognized as a hallmark of the disease. The mitochondrial gatekeeper, voltage-dependent anion channel 1 (VDAC1), mediates transport of metabolites and ions in and out of mitochondria, and is involved in mitochondria-mediated apoptosis. Here...
Autores principales: | Arif, Tasleem, Stern, Oriel, Pittala, Srinivas, Chalifa-Caspi, Vered, Shoshan-Barmatz, Varda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912264/ https://www.ncbi.nlm.nih.gov/pubmed/31661894 http://dx.doi.org/10.3390/cells8111330 |
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