Cargando…

Human iPSCs-Derived Endothelial Cells with Mutation in HNF1A as a Model of Maturity-Onset Diabetes of the Young

Patients with HNF1A-maturity-onset diabetes of the young (MODY) often develop endothelial dysfunction and related microvascular complications, like retinopathy. As the clinical phenotype of HNF1A-MODY diabetes varies considerably, we used human induced pluripotent stem cells (hiPSCs) from two health...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kachamakova-Trojanowska, Neli, Stepniewski, Jacek, Dulak, Jozef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912300/ https://www.ncbi.nlm.nih.gov/pubmed/31739614 http://dx.doi.org/10.3390/cells8111440

Ejemplares similares

Maturity Onset Diabetes of the Young—New Approaches for Disease Modelling
por: Skoczek, Dawid, et al.
Publicado: (2021)

Hypoxia as a Driving Force of Pluripotent Stem Cell Reprogramming and Differentiation to Endothelial Cells
por: Podkalicka, Paulina, et al.
Publicado: (2020)

Lucky iPSCs
por: Zviran, Asaf, et al.
Publicado: (2014)

iPSCs are safe!
por: Yan, Hualong, et al.
Publicado: (2017)

The role of Nrf2 in acute and chronic muscle injury
por: Bronisz-Budzyńska, Iwona, et al.
Publicado: (2020)

CALR frameshift mutations in MPN patient-derived iPSCs accelerate maturation of megakaryocytes
por: Olschok, Kathrin, et al.
Publicado: (2021)

Atorvastatin and Conditioned Media from Atorvastatin-Treated Human Hematopoietic Stem/Progenitor-Derived Cells Show Proangiogenic Activity In Vitro but Not In Vivo
por: Nowak, Witold N., et al.
Publicado: (2019)

Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs
por: Burke, Emily E., et al.
Publicado: (2020)

Targeted Integration of Inducible Caspase-9 in Human iPSCs Allows Efficient in vitro Clearance of iPSCs and iPSC-Macrophages
por: Lipus, Alexandra, et al.
Publicado: (2020)

Mitochondria fingerprint longevity in iPSCs
por: Masotti, Andrea, et al.
Publicado: (2015)

Applications of iPSCs in Cancer Research
por: Kim, Jean J
Publicado: (2015)

Reducing genomic instability in iPSCs
por: Ruiz, Sergio, et al.
Publicado: (2015)

The Challenge of Bringing iPSCs to the Patient
por: Ortuño-Costela, María del Carmen, et al.
Publicado: (2019)

iPSCs in Modeling and Therapy of Osteoarthritis
por: Csobonyeiova, Maria, et al.
Publicado: (2021)

Murine Bone Marrow Lin(−)Sca-1(+)CD45(−) Very Small Embryonic-Like (VSEL) Cells Are Heterogeneous Population Lacking Oct-4A Expression
por: Szade, Krzysztof, et al.
Publicado: (2013)

iPSCs: From Bench to Clinical Bed
por: Li, Yujing, et al.
Publicado: (2016)

Differentiation of human iPSCs into functional podocytes
por: Rauch, Caroline, et al.
Publicado: (2018)

Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes, in Contrast to Adipose Tissue-Derived Stromal Cells, Efficiently Improve Heart Function in Murine Model of Myocardial Infarction
por: Stępniewski, Jacek, et al.
Publicado: (2020)

Identifying the dynamics of actin and tubulin polymerization in iPSCs and in iPSC-derived neurons
por: Magliocca, Valentina, et al.
Publicado: (2017)

Heme Oxygenase-1 May Affect Cell Signalling via Modulation of Ganglioside Composition
por: Šmíd, Václav, et al.
Publicado: (2018)

Modeling HNF1B-associated monogenic diabetes using human iPSCs reveals an early stage impairment of the pancreatic developmental program
por: El-Khairi, Ranna, et al.
Publicado: (2021)

HNF1β Diabetes or Maturity-Onset Diabetes of the Young Type 5 With Rare HNF1β Mutation: A Case Report
por: Haynes, Autumn L., et al.
Publicado: (2019)

Nanog-Independent Reprogramming to iPSCs with Canonical Factors
por: Carter, Ava C., et al.
Publicado: (2014)

Disease, iPSCs and a Quest for the Perfect Model
Publicado: (2016)

Clinical Therapy Using iPSCs: Hopes and Challenges
por: Lu, Xiao, et al.
Publicado: (2013)

The Potential of iPSCs for the Treatment of Premature Aging Disorders
por: Compagnucci, Claudia, et al.
Publicado: (2017)

The tale of autologous iPSCs: A monkey perspective
por: Li, Fei
Publicado: (2014)

Tumorigenicity risk of iPSCs in vivo: nip it in the bud
por: Zhong, Chaoliang, et al.
Publicado: (2022)

Functional genomics and the future of iPSCs in disease modeling
por: Brooks, Imogen R., et al.
Publicado: (2022)

Modelling urea cycle disorders using iPSCs
por: Duff, Claire, et al.
Publicado: (2022)

iPSCs in NK Cell Manufacturing and NKEV Development
por: Boyd-Gibbins, Nicholas, et al.
Publicado: (2022)

MSCs vs. iPSCs: Potential in therapeutic applications
por: Thanaskody, Kalaiselvaan, et al.
Publicado: (2022)

New HNF‐1α nonsense mutation causes maturity‐onset diabetes of the young type 3
por: Nogaroto, Viviane, et al.
Publicado: (2011)

Novel HNF1A gene mutation in maturity-onset diabetes of the young: A case report
por: Xu, Qian, et al.
Publicado: (2022)

Microglia Development and Maturation and Its Implications for Induction of Microglia-Like Cells from Human iPSCs
por: Wurm, Johannes, et al.
Publicado: (2021)

Maturity onset diabetes of the young due to HNF1A variants in Croatia
por: Pavić, Tamara, et al.
Publicado: (2018)

Deficiency in MT5-MMP Supports Branching of Human iPSCs-Derived Neurons and Reduces Expression of GLAST/S100 in iPSCs-Derived Astrocytes
por: Arnst, Nikita, et al.
Publicado: (2021)

HNF4A mutation: switch from hyperinsulinaemic hypoglycaemia to maturity-onset diabetes of the young, and incretin response
por: Arya, V B, et al.
Publicado: (2014)

HNF1A mutation in a Thai patient with maturity-onset diabetes of the young: A case report
por: Plengvidhya, Nattachet, et al.
Publicado: (2019)

Modelling DMD-associated cardiomyopathy in patient-derived iPSCs
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_20ilb0kphv5pj2ffbatm7nahoo