Cargando…

Ending Restenosis: Inhibition of Vascular Smooth Muscle Cell Proliferation by cAMP

Increased vascular smooth muscle cell (VSMC) proliferation contributes towards restenosis after angioplasty, vein graft intimal thickening and atherogenesis. The second messenger 3′ 5′ cyclic adenosine monophosphate (cAMP) plays an important role in maintaining VSMC quiescence in healthy vessels and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smith, Sarah A., Newby, Andrew C., Bond, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912325/ https://www.ncbi.nlm.nih.gov/pubmed/31744111 http://dx.doi.org/10.3390/cells8111447

Ejemplares similares

The Hippo pathway mediates inhibition of vascular smooth muscle cell proliferation by cAMP
por: Kimura, Tomomi E., et al.
Publicado: (2016)

Inhibition of Egr1 expression underlies the anti-mitogenic effects of cAMP in vascular smooth muscle cells
por: Kimura, Tomomi E., et al.
Publicado: (2014)

Divergent Regulation of Actin Dynamics and Megakaryoblastic Leukemia-1 and -2 (Mkl1/2) by cAMP in Endothelial and Smooth Muscle Cells
por: Smith, Madeleine C., et al.
Publicado: (2017)

The cAMP-producing agonist beraprost inhibits human vascular smooth muscle cell migration via exchange protein directly activated by cAMP
por: McKean, Jenny S., et al.
Publicado: (2015)

Eviprostat Activates cAMP Signaling Pathway and Suppresses Bladder Smooth Muscle Cell Proliferation
por: Li, Kai, et al.
Publicado: (2013)

Inhibition of vascular smooth muscle growth via signaling crosstalk between AMP-activated protein kinase and cAMP-dependent protein kinase
por: Stone, Joshua D., et al.
Publicado: (2012)

Transcription factors regulated by cAMP in smooth muscle of the myometrium at human parturition
por: Li, Jonathan K.H., et al.
Publicado: (2021)

Sulfur dioxide inhibits vascular smooth muscle cell proliferation via suppressing the Erk/MAP kinase pathway mediated by cAMP/PKA signaling
por: Liu, D, et al.
Publicado: (2014)

Opening up to cAMP Transport Mechanisms in Airway Smooth Muscle
por: Huff, Ryan D., et al.
Publicado: (2021)

PKA and Epac synergistically inhibit smooth muscle cell proliferation
por: Hewer, Richard C., et al.
Publicado: (2011)

Transcription factor cAMP response element modulator (Crem) restrains Pdgf-dependent proliferation of vascular smooth muscle cells in mice
por: Seidl, M. D., et al.
Publicado: (2014)

Imidazole-induced contractions in bovine tracheal smooth muscle are not dependent on the cAMP pathway
por: KANEDA, Takeharu, et al.
Publicado: (2017)

Selective inhibition of histamine-evoked Ca(2+) signals by compartmentalized cAMP in human bronchial airway smooth muscle cells
por: Dale, Philippa, et al.
Publicado: (2018)

cAMP-induced actin cytoskeleton remodelling inhibits MKL1-dependent expression of the chemotactic and pro-proliferative factor, CCN1
por: Duggirala, Aparna, et al.
Publicado: (2015)

Myostatin Inhibits Vascular Smooth Muscle Cell Proliferation and Local 14q32 microRNA Expression, But Not Systemic Inflammation or Restenosis
por: Goossens, Eveline A.C., et al.
Publicado: (2020)

S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo
por: Wu, Yih-Jer, et al.
Publicado: (2009)

Treprostinil inhibits proliferation and extracellular matrix deposition by fibroblasts through cAMP activation
por: Lambers, Christopher, et al.
Publicado: (2018)

Multiple Facets of cAMP Signalling and Physiological Impact: cAMP Compartmentalization in the Lung
por: Oldenburger, Anouk, et al.
Publicado: (2012)

Lin28a up‐regulation is associated with the formation of restenosis via promoting proliferation and migration of vascular smooth muscle cells
por: Zou, Zhiwei, et al.
Publicado: (2020)

Metabolic benefits of inhibiting cAMP-PDEs with resveratrol
por: Chung, Jay H.
Publicado: (2012)

Soluble adenylyl cyclase links Ca(2+) entry to Ca(2+)/cAMP-response element binding protein (CREB) activation in vascular smooth muscle
por: Parker, Tony, et al.
Publicado: (2019)

Angiogenesis and vasculogenic mimicry are inhibited by 8-Br-cAMP through activation of the cAMP/PKA pathway in colorectal cancer
por: Wang, Sen, et al.
Publicado: (2018)

Alterations of cAMP-dependent signaling in dystrophic skeletal muscle
por: Rudolf, Rüdiger, et al.
Publicado: (2013)

cAMP crosses junctions
por: Bashyam, Hema
Publicado: (2007)

Mitochondrial cAMP signaling
por: Zhang, Fan, et al.
Publicado: (2016)

CNP-pGC-cGMP-PDE3-cAMP Signal Pathway Upregulated in Gastric Smooth Muscle of Diabetic Rats
por: Cai, Ying-Lan, et al.
Publicado: (2015)

Decorin Mimic Inhibits Vascular Smooth Muscle Proliferation and Migration
por: Scott, Rebecca A., et al.
Publicado: (2013)

Zoledronate upregulates MMP-9 and -13 in rat vascular smooth muscle cells by inducing oxidative stress
por: Arun, Mehmet Zuhuri, et al.
Publicado: (2016)

β(2)-Agonist Induced cAMP Is Decreased in Asthmatic Airway Smooth Muscle Due to Increased PDE4D
por: Trian, Thomas, et al.
Publicado: (2011)

Protective Effects of Adiponectin against Cobalt Chloride-Induced Apoptosis of Smooth Muscle Cells via cAMP/PKA Pathway
por: Xiao, Jingjie, et al.
Publicado: (2020)

miRNA-92a inhibits vascular smooth muscle cell phenotypic modulation and may help prevent in-stent restenosis
por: Jiang, Fenfen, et al.
Publicado: (2023)

Smooth Muscle-Alpha Actin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting Rac1 Activity
por: Chen, Lihua, et al.
Publicado: (2016)

cAMP Compartmentalisation in Human Myometrial Cells
por: Varley, Alice, et al.
Publicado: (2023)

Roles of vascular endothelial and smooth muscle cells in the vasculoprotective effect of insulin in a mouse model of restenosis
por: Mori, Yusaku, et al.
Publicado: (2021)

Retinoic acid and cAMP inhibit rat hepatocellular carcinoma cell proliferation and enhance cell differentiation
por: Ionta, M., et al.
Publicado: (2012)

GRIA2/ENPP3 Regulates the Proliferation and Migration of Vascular Smooth Muscle Cells in the Restenosis Process Post-PTA in Lower Extremity Arteries
por: Zhou, Mi, et al.
Publicado: (2021)

Imaging cAMP nanodomains in the heart
por: Chao, Ying-Chi, et al.
Publicado: (2019)

β-Adrenergic cAMP Signals Are Predominantly Regulated by Phosphodiesterase Type 4 in Cultured Adult Rat Aortic Smooth Muscle Cells
por: Zhai, Kui, et al.
Publicado: (2012)

Cyclic 3', 5'-AMP relay in dictyostelium discoideum. IV. Recovery of the cAMP signaling response after adaptation to cAMP
por: Dinauer, M, et al.
Publicado: (1980)

Cyclic 3', 5'-AMP relay dictyostelium discoideum. V. Adaptation of the cAMP signaling response during cAMP stimulation
por: Dinauer, M, et al.
Publicado: (1980)

Cannot write session to /tmp/vufind_sessions/sess_eq436o5bki5bk4lgoqkc2s5b9m