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Development of Oxadiazole-Based ODZ10117 as a Small-Molecule Inhibitor of STAT3 for Targeted Cancer Therapy
Persistently activated STAT3 is a promising target for a new class of anticancer drug development and cancer therapy, as it is associated with tumor initiation, progression, malignancy, drug resistance, cancer stem cell properties, and recurrence. Here, we discovered 3-(2,4-dichloro-phenoxymethyl)-5...
Autores principales: | Kim, Byung-Hak, Lee, Haeri, Song, Yeonghun, Park, Joon-Suk, Gadhe, Changdev G., Choi, Jiwon, Lee, Chung-Gi, Pae, Ae Nim, Kim, Sanghee, Ye, Sang-Kyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912340/ https://www.ncbi.nlm.nih.gov/pubmed/31684051 http://dx.doi.org/10.3390/jcm8111847 |
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