Cargando…

Opposed Actions of PKA Isozymes (RI and RII) and PKC Isoforms (cPKCβI and nPKCε) in Neuromuscular Developmental Synapse Elimination

Background: During neuromuscular junction (NMJ) development, synapses are produced in excess. By sensing the activity-dependent release of ACh, adenosine, and neurotrophins, presynaptic receptors prompt axonal competition and loss of the unnecessary axons. The receptor action is mediated by synergis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Garcia, Neus, Balañà, Cori, Lanuza, Maria A., Tomàs, Marta, Cilleros-Mañé, Víctor, Just-Borràs, Laia, Tomàs, Josep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912401/ https://www.ncbi.nlm.nih.gov/pubmed/31652775 http://dx.doi.org/10.3390/cells8111304

Ejemplares similares

BDNF-TrkB Signaling Coupled to nPKCε and cPKCβI Modulate the Phosphorylation of the Exocytotic Protein Munc18-1 During Synaptic Activity at the Neuromuscular Junction
por: Simó, Anna, et al.
Publicado: (2018)

PKA and PKC Balance in Synapse Elimination during Neuromuscular Junction Development
por: Garcia, Neus, et al.
Publicado: (2021)

Muscle Contraction Regulates BDNF/TrkB Signaling to Modulate Synaptic Function through Presynaptic cPKCα and cPKCβI
por: Hurtado, Erica, et al.
Publicado: (2017)

The Impact of Kinases in Amyotrophic Lateral Sclerosis at the Neuromuscular Synapse: Insights into BDNF/TrkB and PKC Signaling
por: Lanuza, Maria A., et al.
Publicado: (2019)

Synaptic Activity and Muscle Contraction Increases PDK1 and PKCβI Phosphorylation in the Presynaptic Membrane of the Neuromuscular Junction
por: Hurtado, Erica, et al.
Publicado: (2017)

cPKC regulates interphase nuclear size during Xenopus development
por: Edens, Lisa J., et al.
Publicado: (2014)

Statin-specific inhibition of Rab-GTPase regulates cPKC-mediated IKs internalization
por: Ronzier, Elsa, et al.
Publicado: (2019)

Hydrogen Sulfide Protects Against Uremic Accelerated Atherosclerosis via nPKCδ/Akt Signal Pathway
por: Lu, Xiangxue, et al.
Publicado: (2021)

Go-6976 Reverses Hyperglycemia-Induced Insulin Resistance Independently of cPKC Inhibition in Adipocytes
por: Robinson, Katherine A., et al.
Publicado: (2014)

Regulation of Transcriptional Networks by PKC Isozymes: Identification of c-Rel as a Key Transcription Factor for PKC-Regulated Genes
por: Garg, Rachana, et al.
Publicado: (2013)

PKA, PKC, and AKAP localization in and around the neuromuscular junction
por: Perkins, Guy A, et al.
Publicado: (2001)

Diverse dynamics features of novel protein kinase C (PKC) isozymes determine the selectivity of a fluorinated balanol analogue for PKCε
por: Hardianto, Ari, et al.
Publicado: (2019)

PKCα and PKCδ: Friends and Rivals
por: Black, Jennifer D., et al.
Publicado: (2022)

1–42 β-Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death
por: Manterola, L, et al.
Publicado: (2013)

Differential Roles of the PKC Novel Isoforms, PKCδ and PKCε, in Mouse and Human Platelets
por: Pears, Catherine J., et al.
Publicado: (2008)

cPKCγ membrane translocation is involved in herkinorin-induced neuroprotection against cerebral ischemia/reperfusion injury in mice
por: Gui, Xiaochen, et al.
Publicado: (2017)

Paclitaxel Regulates TRPA1 Function and Expression Through PKA and PKC
por: Sánchez, Julio C., et al.
Publicado: (2022)

Protein Kinase C (PKC) Isozymes as Diagnostic and Prognostic Biomarkers and Therapeutic Targets for Cancer
por: Kawano, Takahito, et al.
Publicado: (2022)

Synaptic retrograde regulation of the PKA-induced SNAP-25 and Synapsin-1 phosphorylation
por: Polishchuk, Aleksandra, et al.
Publicado: (2023)

Clematichinenoside Serves as a Neuroprotective Agent Against Ischemic Stroke: The Synergistic Action of ERK1/2 and cPKC Pathways
por: Liu, Chao, et al.
Publicado: (2016)

Monocular Deprivation Affects Visual Cortex Plasticity Through cPKCγ-Modulated GluR1 Phosphorylation in Mice
por: Zhang, Yunxia, et al.
Publicado: (2020)

Molecular mechanisms of hydrogen sulfide against uremic accelerated atherosclerosis through cPKCβII/Akt signal pathway
por: Xiong, Ruifang, et al.
Publicado: (2019)

PKA and ERK, but not PKC, in the amygdala contribute to pain-related synaptic plasticity and behavior
por: Fu, Yu, et al.
Publicado: (2008)

Consecutive pharmacological activation of PKA and PKC mimics the potent cardioprotection of temperature preconditioning
por: Khaliulin, Igor, et al.
Publicado: (2010)

PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells
por: French, Amanda D., et al.
Publicado: (2009)

PKC and PKA Regulate AChR Dynamics at the Neuromuscular Junction of Living Mice
por: Martinez-Pena y Valenzuela, Isabel, et al.
Publicado: (2013)

cPKCγ-Modulated Sequential Reactivation of mTOR Inhibited Autophagic Flux in Neurons Exposed to Oxygen Glucose Deprivation/Reperfusion
por: Hua, Rongrong, et al.
Publicado: (2018)

Effect of the cPKCγ-Ng Signaling System on Rapid Eye Movement Sleep Deprivation-Induced Learning and Memory Impairment in Rats
por: Xu, Shu, et al.
Publicado: (2021)

Retraction: Clematichinenoside Serves as a Neuroprotective Agent Against Ischemic Stroke: The Synergistic Action of ERK1/2 and cPKC Pathways
Publicado: (2021)

An optogenetic tool to recruit individual PKC isozymes to the cell surface and promote specific phosphorylation of membrane proteins
por: Gada, Kirin D., et al.
Publicado: (2022)

Corrigendum: Effect of the cPKCγ-Ng Signaling System on Rapid Eye Movement Sleep Deprivation-Induced Learning and Memory Impairment in Rats
por: Xu, Shu, et al.
Publicado: (2021)

Overexpressed PKCδ Downregulates the Expression of PKCα in B16F10 Melanoma: Induction of Apoptosis by PKCδ via Ceramide Generation
por: Halder, Kuntal, et al.
Publicado: (2014)

Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors
por: Ratnayake, Wishrawana S., et al.
Publicado: (2018)

PKC decodes Ca(2+)
por: LeBrasseur, Nicole
Publicado: (2006)

PKC and calcium channel trafficking
por: Hofmann, Franz
Publicado: (2017)

PKC and PKN in heart disease
por: Marrocco, Valeria, et al.
Publicado: (2019)

cPKCγ‐mediated down‐regulation of UCHL1 alleviates ischaemic neuronal injuries by decreasing autophagy via ERK‐mTOR pathway
por: Zhang, Dan, et al.
Publicado: (2017)

The antifungal protein PAF interferes with PKC/MPK and cAMP/PKA signalling of Aspergillus nidulans
por: Binder, Ulrike, et al.
Publicado: (2010)

Increase in PKCα Activity during Heart Failure Despite the Stimulation of PKCα Braking Mechanism
por: Aslam, Naveed
Publicado: (2020)

Protein kinase C in the wood frog, Rana sylvatica: reassessing the tissue-specific regulation of PKC isozymes during freezing
por: Dieni, Christopher A., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_d50tdccsnplfvcnioeikf7cetp