Akt1 and Akt2 Isoforms Play Distinct Roles in Regulating the Development of Inflammation and Fibrosis Associated with Alcoholic Liver Disease

Akt kinase isoforms (Akt1, Akt2, and Akt3) have generally been thought to play overlapping roles in phosphoinositide 3-kinase (PI3K)-mediated-signaling. However, recent studies have suggested that they display isoform-specific roles in muscle and fat. To determine whether such isoform-specificity is...

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Detalles Bibliográficos
Autores principales: Reyes-Gordillo, Karina, Shah, Ruchi, Arellanes-Robledo, Jaime, Cheng, Ying, Ibrahim, Joseph, Tuma, Pamela L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912497/
https://www.ncbi.nlm.nih.gov/pubmed/31671832
http://dx.doi.org/10.3390/cells8111337

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