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CCN2 Mediates S1P-Induced Upregulation of COX2 Expression in Human Granulosa-Lutein Cells

CCN1 and CCN2 are members of the CCN family and play essential roles in the regulation of multiple female reproductive functions, including ovulation. Cyclooxygenase-2 (COX2) is a critical mediator of ovulation and can be induced by sphingosine-1-phosphate (S1P) through the S1P(1/3)-mediated Yes-ass...

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Detalles Bibliográficos
Autores principales: Hu, Liao-Liao, Chang, Hsun-Ming, Yi, Yuyin, Liu, Yingtao, Taylor, Elizabeth L., Zheng, Li-Ping, Leung, Peter C.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912539/
https://www.ncbi.nlm.nih.gov/pubmed/31731760
http://dx.doi.org/10.3390/cells8111445

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