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Syntaxin-17-Dependent Mitochondrial Dynamics Is Essential for Protection against Oxidative-Stress-Induced Apoptosis

In this study, cell death induced by the oxidant tert-butylhydroperoxide (tBH) was observed in U(2)OS cells; this phenotype was rescued by Syntaxin 17 (STX17) knockout (KO) but the mechanism is unknown. STX17 plays dual roles in autophagosome–lysosome fusion and mitochondrial fission. However, the c...

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Detalles Bibliográficos
Autores principales:	Wang, Binran, Xiao, Xiaoyue, Huang, Fanwei, Liu, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912610/ https://www.ncbi.nlm.nih.gov/pubmed/31671682 http://dx.doi.org/10.3390/antiox8110522

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