Cholest-4,6-Dien-3-One Promote Epithelial-To-Mesenchymal Transition (EMT) in Biliary Tree Stem/Progenitor Cell Cultures In Vitro

Human biliary tree stem/progenitor cells (hBTSCs), reside in peribiliary glands, are mainly stimulated by primary sclerosing cholangitis (PSC) and cholangiocarcinoma. In these pathologies, hBTSCs displayed epithelial-to-mesenchymal transition (EMT), senescence characteristics, and impaired different...

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Detalles Bibliográficos
Autores principales: Nevi, Lorenzo, Costantini, Daniele, Safarikia, Samira, Di Matteo, Sabina, Melandro, Fabio, Berloco, Pasquale Bartolomeo, Cardinale, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912632/
https://www.ncbi.nlm.nih.gov/pubmed/31731674
http://dx.doi.org/10.3390/cells8111443

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