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Recent Trends in Bacteriology of Adult Patients with Chronic Rhinosinusitis

This study aimed to identify trends in bacteria isolated from Korean adults with chronic rhinosinusitis (CRS). Enrolled were CRS patients who underwent sinus bacterial culture during endoscopic sinus surgery between 2007–2008, 2011–2012, and 2017–2018 (n = 510). Patients’ clinical characteristics, b...

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Autores principales: Kim, Doyeon, Assiri, Abdullah M., Kim, Ji Heui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912634/
https://www.ncbi.nlm.nih.gov/pubmed/31698781
http://dx.doi.org/10.3390/jcm8111889
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author Kim, Doyeon
Assiri, Abdullah M.
Kim, Ji Heui
author_facet Kim, Doyeon
Assiri, Abdullah M.
Kim, Ji Heui
author_sort Kim, Doyeon
collection PubMed
description This study aimed to identify trends in bacteria isolated from Korean adults with chronic rhinosinusitis (CRS). Enrolled were CRS patients who underwent sinus bacterial culture during endoscopic sinus surgery between 2007–2008, 2011–2012, and 2017–2018 (n = 510). Patients’ clinical characteristics, bacterial culture results, and antibiotic resistance were reviewed. The bacteria isolation rate was 76.3% (73.9% for CRS with nasal polyps and 82.8% for CRS without nasal polyps; p = 0.038). In total, 650 strains were isolated, the most common was Coagulase Negative Staphylococci (CNS) (28.0%), followed by Streptococcus species (12.2%), Propionibacterium species (8.0%), Corynebacterium species (7.5%), Staphylococcus aureus (6.2%), Haemophilus species (5.7%), Klebsiella species (5.1%), and Pseudomonas aeruginosa (4.2%). Furthermore, an analysis of the bacterial trends in the three groups showed significant increases over time for the isolation of CNS (p = 0.006), Klebsiella (p = 0.002), and P. aeruginosa (p = 0.007) and extended-spectrum beta-lactamase (ESBL) producing Klebsiella (p < 0.001) and Enterobacter (p = 0.007) species in terms of antibiotics resistance. This study demonstrates that the frequency of CNS, Klebsiella, and P. aeruginosa in CRS patients and the ESBL-producing Klebsiella and Enterobacter species has significantly increased in CRS patients over the last decade.
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spelling pubmed-69126342020-01-02 Recent Trends in Bacteriology of Adult Patients with Chronic Rhinosinusitis Kim, Doyeon Assiri, Abdullah M. Kim, Ji Heui J Clin Med Article This study aimed to identify trends in bacteria isolated from Korean adults with chronic rhinosinusitis (CRS). Enrolled were CRS patients who underwent sinus bacterial culture during endoscopic sinus surgery between 2007–2008, 2011–2012, and 2017–2018 (n = 510). Patients’ clinical characteristics, bacterial culture results, and antibiotic resistance were reviewed. The bacteria isolation rate was 76.3% (73.9% for CRS with nasal polyps and 82.8% for CRS without nasal polyps; p = 0.038). In total, 650 strains were isolated, the most common was Coagulase Negative Staphylococci (CNS) (28.0%), followed by Streptococcus species (12.2%), Propionibacterium species (8.0%), Corynebacterium species (7.5%), Staphylococcus aureus (6.2%), Haemophilus species (5.7%), Klebsiella species (5.1%), and Pseudomonas aeruginosa (4.2%). Furthermore, an analysis of the bacterial trends in the three groups showed significant increases over time for the isolation of CNS (p = 0.006), Klebsiella (p = 0.002), and P. aeruginosa (p = 0.007) and extended-spectrum beta-lactamase (ESBL) producing Klebsiella (p < 0.001) and Enterobacter (p = 0.007) species in terms of antibiotics resistance. This study demonstrates that the frequency of CNS, Klebsiella, and P. aeruginosa in CRS patients and the ESBL-producing Klebsiella and Enterobacter species has significantly increased in CRS patients over the last decade. MDPI 2019-11-06 /pmc/articles/PMC6912634/ /pubmed/31698781 http://dx.doi.org/10.3390/jcm8111889 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kim, Doyeon
Assiri, Abdullah M.
Kim, Ji Heui
Recent Trends in Bacteriology of Adult Patients with Chronic Rhinosinusitis
title Recent Trends in Bacteriology of Adult Patients with Chronic Rhinosinusitis
title_full Recent Trends in Bacteriology of Adult Patients with Chronic Rhinosinusitis
title_fullStr Recent Trends in Bacteriology of Adult Patients with Chronic Rhinosinusitis
title_full_unstemmed Recent Trends in Bacteriology of Adult Patients with Chronic Rhinosinusitis
title_short Recent Trends in Bacteriology of Adult Patients with Chronic Rhinosinusitis
title_sort recent trends in bacteriology of adult patients with chronic rhinosinusitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912634/
https://www.ncbi.nlm.nih.gov/pubmed/31698781
http://dx.doi.org/10.3390/jcm8111889
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