Estrogen Receptors and Melanoma: A Review

In the last three decades cutaneous melanoma has been widely investigated as a steroid hormone-sensitive cancer. Following this hypothesis, many epidemiological studies have investigated the relationship between estrogens and melanoma. No evidence to date has supported this association due to the gr...

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Detalles Bibliográficos
Autores principales: Dika, Emi, Patrizi, Annalisa, Lambertini, Martina, Manuelpillai, Nicholas, Fiorentino, Michelangelo, Altimari, Annalisa, Ferracin, Manuela, Lauriola, Mattia, Fabbri, Enrica, Campione, Elena, Veronesi, Giulia, Scarfì, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912660/
https://www.ncbi.nlm.nih.gov/pubmed/31752344
http://dx.doi.org/10.3390/cells8111463
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author Dika, Emi
Patrizi, Annalisa
Lambertini, Martina
Manuelpillai, Nicholas
Fiorentino, Michelangelo
Altimari, Annalisa
Ferracin, Manuela
Lauriola, Mattia
Fabbri, Enrica
Campione, Elena
Veronesi, Giulia
Scarfì, Federica
author_facet Dika, Emi
Patrizi, Annalisa
Lambertini, Martina
Manuelpillai, Nicholas
Fiorentino, Michelangelo
Altimari, Annalisa
Ferracin, Manuela
Lauriola, Mattia
Fabbri, Enrica
Campione, Elena
Veronesi, Giulia
Scarfì, Federica
author_sort Dika, Emi
collection PubMed
description In the last three decades cutaneous melanoma has been widely investigated as a steroid hormone-sensitive cancer. Following this hypothesis, many epidemiological studies have investigated the relationship between estrogens and melanoma. No evidence to date has supported this association due to the great complexity of genetic, external and environmental factors underlying the development of this cancer. Molecular mechanisms through which estrogen and their receptor exert a role in melanoma genesis are still under investigation with new studies increasingly focusing on the discovery of new molecular targets for therapeutic treatments.
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spelling pubmed-69126602020-01-02 Estrogen Receptors and Melanoma: A Review Dika, Emi Patrizi, Annalisa Lambertini, Martina Manuelpillai, Nicholas Fiorentino, Michelangelo Altimari, Annalisa Ferracin, Manuela Lauriola, Mattia Fabbri, Enrica Campione, Elena Veronesi, Giulia Scarfì, Federica Cells Review In the last three decades cutaneous melanoma has been widely investigated as a steroid hormone-sensitive cancer. Following this hypothesis, many epidemiological studies have investigated the relationship between estrogens and melanoma. No evidence to date has supported this association due to the great complexity of genetic, external and environmental factors underlying the development of this cancer. Molecular mechanisms through which estrogen and their receptor exert a role in melanoma genesis are still under investigation with new studies increasingly focusing on the discovery of new molecular targets for therapeutic treatments. MDPI 2019-11-19 /pmc/articles/PMC6912660/ /pubmed/31752344 http://dx.doi.org/10.3390/cells8111463 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Dika, Emi
Patrizi, Annalisa
Lambertini, Martina
Manuelpillai, Nicholas
Fiorentino, Michelangelo
Altimari, Annalisa
Ferracin, Manuela
Lauriola, Mattia
Fabbri, Enrica
Campione, Elena
Veronesi, Giulia
Scarfì, Federica
Estrogen Receptors and Melanoma: A Review
title Estrogen Receptors and Melanoma: A Review
title_full Estrogen Receptors and Melanoma: A Review
title_fullStr Estrogen Receptors and Melanoma: A Review
title_full_unstemmed Estrogen Receptors and Melanoma: A Review
title_short Estrogen Receptors and Melanoma: A Review
title_sort estrogen receptors and melanoma: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912660/
https://www.ncbi.nlm.nih.gov/pubmed/31752344
http://dx.doi.org/10.3390/cells8111463
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