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The liver injury following ischemia and reperfusion is worse in experimental knockout heterozygote mouse model for expression of connexin 43()

PURPOSE: To evaluate that Connexin (Cx43) plays a role in lesions after hepatic ischemia/reperfusion (IR) injury. METHODS: We use Cx43 deficient model (heterozygotes mice) and compared to a wild group. The groups underwent 1 hour ischemia and 24 hours reperfusion. The heterozygote genotype was confi...

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Detalles Bibliográficos
Autores principales: Trevisan, Alexandre Maximiliano, Cogliati, Bruno, Homem, Adriana Ribeiro, Aloiav, Thiago Pinheiro Arrais, de Aquino, Nelson, Moreira, Jairo Marques, Reno, Leonardo da Cruz, Naumann, Alexandre Moulin, Galvão, Flavio Henrique Ferreira, Andraus, Wellington, D'Albuquerque, Luiz Augusto Carneiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912844/
https://www.ncbi.nlm.nih.gov/pubmed/31851211
http://dx.doi.org/10.1590/s0102-865020190100000003

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