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The effect of 5α-oleandrin on keloid fibroblast activities
BACKGROUND: Keloids develop due to hyperactivity of keloid fibroblast (KF) in proliferation, migration, and collagen deposition along with low rates of collagen degradation. These are a result of the Wnt/β catenin signaling pathways under stimulation of TGF-β. 5α-oleandrin can suppress Wnt-targeted...
Autores principales: | Dachlan, Ishandono, Wirohadidjojo, Yohanes Widodo, Wahyuningsih, Mae Sri Hartati, Aryandono, Teguh, Soebono, Hardyanto, Afandy, Dwiki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912934/ https://www.ncbi.nlm.nih.gov/pubmed/31890007 http://dx.doi.org/10.1186/s12919-019-0177-6 |
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