Predicting associations among drugs, targets and diseases by tensor decomposition for drug repositioning

BACKGROUND: Development of new drugs is a time-consuming and costly process, and the cost is still increasing in recent years. However, the number of drugs approved by FDA every year per dollar spent on development is declining. Drug repositioning, which aims to find new use of existing drugs, attra...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ran, Li, Shuai, Cheng, Lixin, Wong, Man Hon, Leung, Kwong Sak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912989/
https://www.ncbi.nlm.nih.gov/pubmed/31839008
http://dx.doi.org/10.1186/s12859-019-3283-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912989/
https://www.ncbi.nlm.nih.gov/pubmed/31839008
http://dx.doi.org/10.1186/s12859-019-3283-6

Ejemplares similares